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CD44 inhibition attenuates EGFR signaling and enhances cisplatin sensitivity in human EGFR wild-type non-small-cell lung cancer cells

Cluster of differentiation 44 (CD44) as a transmembrane glycoprotein is found to be expressed in non-small cell lung cancer (NSCLC), is significantly associated with NSLC progression, metastasis and drug resistance. This study aimed to explore whether CD44 inhibition improves the sensitivity of epid...

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Detalles Bibliográficos
Autores principales: Yin, Jianhua, Zhang, Hanyu, Wu, Xu, Zhang, Yuchen, Li, Jing, Shen, Jing, Zhao, Yueshui, Xiao, Zhangang, Lu, Lan, Huang, Chengliang, Zhang, Zhuo, Du, Fukuan, Wu, Yuanlin, Kaboli, Parham Jabbarzadeh, Cho, Chi Hin, Yuan, Dandan, Li, Mingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169661/
https://www.ncbi.nlm.nih.gov/pubmed/32236608
http://dx.doi.org/10.3892/ijmm.2020.4562