A comprehensive microbiological safety approach for agarose encapsulated porcine islets intended for clinical trials

BACKGROUND: The use of porcine islets to replace insulin‐producing islet β‐cells, destroyed during the diabetogenic disease process, presents distinct challenges if this option is to become a therapeutic reality for the treatment of type 1 diabetes. These challenges include a thorough evaluation of...

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Detalles Bibliográficos
Autores principales: Gazda, Lawrence S., Collins, James, Lovatt, Archie, Holdcraft, Robert W., Morin, Merribeth J., Galbraith, Daniel, Graham, Melanie, Laramore, Melissa A., Maclean, Christine, Black, John, Milne, Euan W., Marthaler, Douglas G., Vinerean, Horatiu V., Michalak, Michelle M., Hoffer, Deborah, Richter, Steven, Hall, Richard D., Smith, Barry H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169751/
https://www.ncbi.nlm.nih.gov/pubmed/27862363
http://dx.doi.org/10.1111/xen.12277

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