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Increased prevalence of endocervical Mycoplasma and Ureaplasma colonization in infertile women with tubal factor
OBJECTIVE: Most women suffering from tubal factor infertility do not have a history of pelvic inflammatory disease, but rather have asymptomatic upper genital tract infection. Investigating the impacts of such infections, even in the absence of clinically confirmed pelvic inflammatory disease, is cr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Brazilian Society of Assisted Reproduction
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169909/ https://www.ncbi.nlm.nih.gov/pubmed/32031768 http://dx.doi.org/10.5935/1518-0557.20190078 |
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author | Piscopo, Rita CCP Guimarães, Ronney V Ueno, Joji Ikeda, Fabio Bella, Zsuzsanna IK Jarmy-Di Girão, Manoel JBC Samama, Marise |
author_facet | Piscopo, Rita CCP Guimarães, Ronney V Ueno, Joji Ikeda, Fabio Bella, Zsuzsanna IK Jarmy-Di Girão, Manoel JBC Samama, Marise |
author_sort | Piscopo, Rita CCP |
collection | PubMed |
description | OBJECTIVE: Most women suffering from tubal factor infertility do not have a history of pelvic inflammatory disease, but rather have asymptomatic upper genital tract infection. Investigating the impacts of such infections, even in the absence of clinically confirmed pelvic inflammatory disease, is critical to understanding the tubal factor of infertility. The aim of this study was to investigate whether the presence of endocervical bacteria is associated with tubal factors in women screened for infertility. METHODS: This retrospective cross-sectional study involved 245 women undergoing hysterosalpingography (HSG), screened for endocervical colonization by Chlamydia trachomatis, Neisseria gonorrhea, Ureaplasma urealyticum and Mycoplasma hominis, as part of a routine female infertility investigation between 2016 and 2017. RESULTS: endocervical bacterial colonization by Chlamydia trachomatis, Ureaplasma urealiticum, Mycoplasma hominis and other bacteria corresponded to 3.7%, 9.0%; 5.7% and 9.8%, respectively. There was no colonization by Neisseria gonorrhea. The prevalence of tubal factor was significantly higher in patients with positive endocervical bacteria colonization, regardless of bacterial species. When evaluating bacteria species individually, the women who were positive for endocervical Mycoplasma hominis had significantly higher rates of tubal factor. Associations between endocervical bacterial colonization and tubal factor infertility were confirmed by multiple regression analysis adjusted for age and duration of infertility. CONCLUSION: Besides the higher prevalence of Mycoplasma and Ureaplasma infectious agents, the findings of this study suggest the possible association of endocervical bacterial colonization - not only Chlamydia trachomatis and Neisseria gonorrhea, but also Mycoplasma species with tubal performance. |
format | Online Article Text |
id | pubmed-7169909 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Brazilian Society of Assisted Reproduction |
record_format | MEDLINE/PubMed |
spelling | pubmed-71699092020-04-24 Increased prevalence of endocervical Mycoplasma and Ureaplasma colonization in infertile women with tubal factor Piscopo, Rita CCP Guimarães, Ronney V Ueno, Joji Ikeda, Fabio Bella, Zsuzsanna IK Jarmy-Di Girão, Manoel JBC Samama, Marise JBRA Assist Reprod Original Article OBJECTIVE: Most women suffering from tubal factor infertility do not have a history of pelvic inflammatory disease, but rather have asymptomatic upper genital tract infection. Investigating the impacts of such infections, even in the absence of clinically confirmed pelvic inflammatory disease, is critical to understanding the tubal factor of infertility. The aim of this study was to investigate whether the presence of endocervical bacteria is associated with tubal factors in women screened for infertility. METHODS: This retrospective cross-sectional study involved 245 women undergoing hysterosalpingography (HSG), screened for endocervical colonization by Chlamydia trachomatis, Neisseria gonorrhea, Ureaplasma urealyticum and Mycoplasma hominis, as part of a routine female infertility investigation between 2016 and 2017. RESULTS: endocervical bacterial colonization by Chlamydia trachomatis, Ureaplasma urealiticum, Mycoplasma hominis and other bacteria corresponded to 3.7%, 9.0%; 5.7% and 9.8%, respectively. There was no colonization by Neisseria gonorrhea. The prevalence of tubal factor was significantly higher in patients with positive endocervical bacteria colonization, regardless of bacterial species. When evaluating bacteria species individually, the women who were positive for endocervical Mycoplasma hominis had significantly higher rates of tubal factor. Associations between endocervical bacterial colonization and tubal factor infertility were confirmed by multiple regression analysis adjusted for age and duration of infertility. CONCLUSION: Besides the higher prevalence of Mycoplasma and Ureaplasma infectious agents, the findings of this study suggest the possible association of endocervical bacterial colonization - not only Chlamydia trachomatis and Neisseria gonorrhea, but also Mycoplasma species with tubal performance. Brazilian Society of Assisted Reproduction 2020 /pmc/articles/PMC7169909/ /pubmed/32031768 http://dx.doi.org/10.5935/1518-0557.20190078 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Piscopo, Rita CCP Guimarães, Ronney V Ueno, Joji Ikeda, Fabio Bella, Zsuzsanna IK Jarmy-Di Girão, Manoel JBC Samama, Marise Increased prevalence of endocervical Mycoplasma and Ureaplasma colonization in infertile women with tubal factor |
title | Increased prevalence of endocervical Mycoplasma and Ureaplasma colonization in infertile women with tubal factor |
title_full | Increased prevalence of endocervical Mycoplasma and Ureaplasma colonization in infertile women with tubal factor |
title_fullStr | Increased prevalence of endocervical Mycoplasma and Ureaplasma colonization in infertile women with tubal factor |
title_full_unstemmed | Increased prevalence of endocervical Mycoplasma and Ureaplasma colonization in infertile women with tubal factor |
title_short | Increased prevalence of endocervical Mycoplasma and Ureaplasma colonization in infertile women with tubal factor |
title_sort | increased prevalence of endocervical mycoplasma and ureaplasma colonization in infertile women with tubal factor |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169909/ https://www.ncbi.nlm.nih.gov/pubmed/32031768 http://dx.doi.org/10.5935/1518-0557.20190078 |
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