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CDK5 inhibition in vitro and in vivo induces cell death in myeloma and overcomes the obstacle of bortezomib resistance
The emergence of new drugs is a major feature of the treatment history of multiple myeloma (MM), which also reflects the current incurability of MM. As a unique member of cyclin dependent kinase (CDK) family, CDK5 participates in numerous tumorigenic or non-tumorigenic processes. The aim of this stu...
Autores principales: | Tang, Hailong, Xu, Li, Cen, Xi, Yang, Li, Feng, Juan, Li, Guang, Zhu, Huafeng, Gao, Shan, Yu, Yan, Zhao, Yaping, Tian, Zhiqiang, Hou, Liping, Yu, Shuchun, Gao, Guangxun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169959/ https://www.ncbi.nlm.nih.gov/pubmed/32236619 http://dx.doi.org/10.3892/ijmm.2020.4553 |
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