Mitochondrial lipoylation integrates age-associated decline in brown fat thermogenesis

Thermogenesis in brown adipose tissue (BAT) declines with age; however, what regulates this process remains poorly understood. Here, we identify mitochondria lipoylation as a previously unappreciated molecular hallmark of aged BAT in mice. Using mitochondrial proteomics, we show that mitochondrial l...

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Detalles Bibliográficos
Autores principales: Tajima, Kazuki, Ikeda, Kenji, Chang, Hsin-Yi, Chang, Chih-Hsiang, Yoneshiro, Takeshi, Oguri, Yasuo, Jun, Heejin, Wu, Jun, Ishihama, Yasushi, Kajimura, Shingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169975/
https://www.ncbi.nlm.nih.gov/pubmed/32313871
http://dx.doi.org/10.1038/s42255-019-0106-z

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