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Mutational spectrum and classification of novel mutations in patients with metastatic gastrointestinal stromal tumours

In total, ~85% of malignant gastrointestinal stromal tumours (GISTs) harbour activating mutations in one of the genes KIT or PDGFRA, while 10-15% of all GISTs have no detectable KIT or PDGFRA mutations, but could have alterations in genes of the succinate dehydrogenase complex or in BRAF, PIK3CA or...

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Detalles Bibliográficos
Autores principales:	Bombac, Alenka, Zakotnik, Branko, Bucic, Marina, Dragos, Vita Setrajcic, Gazic, Barbara, Stegel, Vida, Klancar, Gasper, Novakovic, Srdjan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170035/ https://www.ncbi.nlm.nih.gov/pubmed/32236636 http://dx.doi.org/10.3892/ijo.2020.5028

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