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Dynamic gating window technique for the reduction of dosimetric error in respiratory‐gated spot‐scanning particle therapy: An initial phantom study using patient tumor trajectory data

Spot‐scanning particle therapy possesses advantages, such as high conformity to the target and efficient energy utilization compared with those of the passive scattering irradiation technique. However, this irradiation technique is sensitive to target motion. In the current clinical situation, some...

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Autores principales: Miyamoto, Naoki, Yokokawa, Kouhei, Takao, Seishin, Matsuura, Taeko, Tanaka, Sodai, Shimizu, Shinichi, Shirato, Hiroki, Umegaki, Kikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170289/
https://www.ncbi.nlm.nih.gov/pubmed/32068347
http://dx.doi.org/10.1002/acm2.12832
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author Miyamoto, Naoki
Yokokawa, Kouhei
Takao, Seishin
Matsuura, Taeko
Tanaka, Sodai
Shimizu, Shinichi
Shirato, Hiroki
Umegaki, Kikuo
author_facet Miyamoto, Naoki
Yokokawa, Kouhei
Takao, Seishin
Matsuura, Taeko
Tanaka, Sodai
Shimizu, Shinichi
Shirato, Hiroki
Umegaki, Kikuo
author_sort Miyamoto, Naoki
collection PubMed
description Spot‐scanning particle therapy possesses advantages, such as high conformity to the target and efficient energy utilization compared with those of the passive scattering irradiation technique. However, this irradiation technique is sensitive to target motion. In the current clinical situation, some motion management techniques, such as respiratory‐gated irradiation, which uses an external or internal surrogate, have been clinically applied. In surrogate‐based gating, the size of the gating window is fixed during the treatment in the current treatment system. In this study, we propose a dynamic gating window technique, which optimizes the size of gating window for each spot by considering a possible dosimetric error. The effectiveness of the dynamic gating window technique was evaluated by simulating irradiation using a moving target in a water phantom. In dosimetric characteristics comparison, the dynamic gating window technique exhibited better performance in all evaluation volumes with different effective depths compared with that of the fixed gate approach. The variation of dosimetric characteristics according to the target depth was small in dynamic gate compared to fixed gate. These results suggest that the dynamic gating window technique can maintain an acceptable dose distribution regardless of the target depth. The overall gating efficiency of the dynamic gate was approximately equal or greater than that of the fixed gating window. In dynamic gate, as the target depth becomes shallower, the gating efficiency will be reduced, although dosimetric characteristics will be maintained regardless of the target depth. The results of this study suggest that the proposed gating technique may potentially improve the dose distribution. However, additional evaluations should be undertaken in the future to determine clinical applicability by assuming the specifications of the treatment system and clinical situation.
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spelling pubmed-71702892020-04-21 Dynamic gating window technique for the reduction of dosimetric error in respiratory‐gated spot‐scanning particle therapy: An initial phantom study using patient tumor trajectory data Miyamoto, Naoki Yokokawa, Kouhei Takao, Seishin Matsuura, Taeko Tanaka, Sodai Shimizu, Shinichi Shirato, Hiroki Umegaki, Kikuo J Appl Clin Med Phys Radiation Oncology Physics Spot‐scanning particle therapy possesses advantages, such as high conformity to the target and efficient energy utilization compared with those of the passive scattering irradiation technique. However, this irradiation technique is sensitive to target motion. In the current clinical situation, some motion management techniques, such as respiratory‐gated irradiation, which uses an external or internal surrogate, have been clinically applied. In surrogate‐based gating, the size of the gating window is fixed during the treatment in the current treatment system. In this study, we propose a dynamic gating window technique, which optimizes the size of gating window for each spot by considering a possible dosimetric error. The effectiveness of the dynamic gating window technique was evaluated by simulating irradiation using a moving target in a water phantom. In dosimetric characteristics comparison, the dynamic gating window technique exhibited better performance in all evaluation volumes with different effective depths compared with that of the fixed gate approach. The variation of dosimetric characteristics according to the target depth was small in dynamic gate compared to fixed gate. These results suggest that the dynamic gating window technique can maintain an acceptable dose distribution regardless of the target depth. The overall gating efficiency of the dynamic gate was approximately equal or greater than that of the fixed gating window. In dynamic gate, as the target depth becomes shallower, the gating efficiency will be reduced, although dosimetric characteristics will be maintained regardless of the target depth. The results of this study suggest that the proposed gating technique may potentially improve the dose distribution. However, additional evaluations should be undertaken in the future to determine clinical applicability by assuming the specifications of the treatment system and clinical situation. John Wiley and Sons Inc. 2020-02-18 /pmc/articles/PMC7170289/ /pubmed/32068347 http://dx.doi.org/10.1002/acm2.12832 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Miyamoto, Naoki
Yokokawa, Kouhei
Takao, Seishin
Matsuura, Taeko
Tanaka, Sodai
Shimizu, Shinichi
Shirato, Hiroki
Umegaki, Kikuo
Dynamic gating window technique for the reduction of dosimetric error in respiratory‐gated spot‐scanning particle therapy: An initial phantom study using patient tumor trajectory data
title Dynamic gating window technique for the reduction of dosimetric error in respiratory‐gated spot‐scanning particle therapy: An initial phantom study using patient tumor trajectory data
title_full Dynamic gating window technique for the reduction of dosimetric error in respiratory‐gated spot‐scanning particle therapy: An initial phantom study using patient tumor trajectory data
title_fullStr Dynamic gating window technique for the reduction of dosimetric error in respiratory‐gated spot‐scanning particle therapy: An initial phantom study using patient tumor trajectory data
title_full_unstemmed Dynamic gating window technique for the reduction of dosimetric error in respiratory‐gated spot‐scanning particle therapy: An initial phantom study using patient tumor trajectory data
title_short Dynamic gating window technique for the reduction of dosimetric error in respiratory‐gated spot‐scanning particle therapy: An initial phantom study using patient tumor trajectory data
title_sort dynamic gating window technique for the reduction of dosimetric error in respiratory‐gated spot‐scanning particle therapy: an initial phantom study using patient tumor trajectory data
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170289/
https://www.ncbi.nlm.nih.gov/pubmed/32068347
http://dx.doi.org/10.1002/acm2.12832
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