Synthesis and biological evaluation of (3/4-(pyrimidin-2-ylamino)benzoyl)-based hydrazine-1-carboxamide/carbothioamide derivatives as novel RXRα antagonists

Abnormal alterations in the expression and biological function of retinoid X receptor alpha (RXRα) have a key role in the development of cancer. Potential modulators of RXRα as anticancer agents are explored in growing numbers of studies. A series of (4/3-(pyrimidin-2-ylamino)benzoyl)hydrazine-1-car...

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Detalles Bibliográficos
Autores principales: Qin, Jingbo, Liu, Jie, Wu, Chunxiao, Xu, Jianwen, Tang, Bowen, Guo, Kaiqiang, Chen, Xiaohui, Liu, Weihao, Wu, Tong, Zhou, Hu, Fang, Meijuan, Wu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170311/
https://www.ncbi.nlm.nih.gov/pubmed/32223461
http://dx.doi.org/10.1080/14756366.2020.1740692

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