Cargando…

Competing endogenous RNA network profiling reveals novel host dependency factors required for MERS-CoV propagation

Circular RNAs (circRNAs) are an integral component of the host competitive endogenous RNA (ceRNA) network. These noncoding RNAs are characterized by their unique splicing reactions to form covalently closed loop structures and play important RNA regulatory roles in cells. Recent studies showed that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xi, Chu, Hin, Wen, Lei, Shuai, Huiping, Yang, Dong, Wang, Yixin, Hou, Yuxin, Zhu, Zheng, Yuan, Shuofeng, Yin, Feifei, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170352/ https://www.ncbi.nlm.nih.gov/pubmed/32223537 http://dx.doi.org/10.1080/22221751.2020.1738277

Ejemplares similares

hnRNP C modulates MERS-CoV and SARS-CoV-2 replication by governing the expression of a subset of circRNAs and cognitive mRNAs
por: Zhang, Xi, et al.
Publicado: (2022)

Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesis
por: Zhou, Jie, et al.
Publicado: (2015)

Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication
por: Yan, Bingpeng, et al.
Publicado: (2019)

Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target
por: Li, Cun, et al.
Publicado: (2020)

Differential immune activation profile of SARS-CoV-2 and SARS-CoV infection in human lung and intestinal cells: Implications for treatment with IFN-β and IFN inducer
por: Shuai, Huiping, et al.
Publicado: (2020)

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2020)

Altered host protease determinants for SARS-CoV-2 Omicron
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2023)

Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells
por: Chu, Hin, et al.
Publicado: (2018)

Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy
por: Zhu, Zheng, et al.
Publicado: (2019)

The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2018)

Severe fever with thrombocytopenia syndrome virus (SFTSV)-host interactome screen identifies viral nucleoprotein-associated host factors as potential antiviral targets
por: Cao, Jianli, et al.
Publicado: (2021)

Host genes and influenza pathogenesis in humans: an emerging paradigm
por: To, Kelvin Kai-Wang, et al.
Publicado: (2015)

Identification and characterization of GLDC as host susceptibility gene to severe influenza
por: Zhou, Jie, et al.
Publicado: (2018)

From SARS to MERS and Ebola
por: Yuen, Kwok Yung
Publicado: (2015)

Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2
por: Hu, Bingjie, et al.
Publicado: (2022)

Age-associated SARS-CoV-2 breakthrough infection and changes in immune response in a mouse model
por: Chen, Yanxia, et al.
Publicado: (2022)

1899. The Cellular Kinase Inhibitor OSU-03012 Inhibits Enterovirus 71 In Vitro
por: Chan, Jasper, et al.
Publicado: (2018)

SARS-CoV-2 exploits host DGAT and ADRP for efficient replication
por: Yuan, Shuofeng, et al.
Publicado: (2021)

A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2022)

Cellular Sensors and Viral Countermeasures: A Molecular Arms Race between Host and SARS-CoV-2
por: Sun, Haoran, et al.
Publicado: (2023)

Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19)
por: Yuan, Shuofeng, et al.
Publicado: (2020)

Host and viral determinants for efficient SARS-CoV-2 infection of the human lung
por: Chu, Hin, et al.
Publicado: (2021)

Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity
por: Chu, Hin, et al.
Publicado: (2021)

Rapid detection of MERS coronavirus-like viruses in bats: potential for tracking MERS coronavirus transmission and animal origin
por: Woo, Patrick C. Y., et al.
Publicado: (2018)

Metabolic Profiling Reveals Significant Perturbations of Intracellular Glucose Homeostasis in Enterovirus-Infected Cells
por: Zou, Zijiao, et al.
Publicado: (2020)

Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza
por: Zhao, Hanjun, et al.
Publicado: (2018)

Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters
por: Zhang, Anna Jinxia, et al.
Publicado: (2020)

STAT2-dependent restriction of Zika virus by human macrophages but not dendritic cells
por: Yang, Dong, et al.
Publicado: (2021)

Lipidomic Profiling Reveals Significant Perturbations of Intracellular Lipid Homeostasis in Enterovirus-Infected Cells
por: Yan, Bingpeng, et al.
Publicado: (2019)

Fatal anti-aquaporin-4 seropositive neuromyelitis optica spectrum disorder in tuberculosis
por: Sridhar, Siddharth, et al.
Publicado: (2014)

Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target
por: Yuan, Shuofeng, et al.
Publicado: (2020)

Development of Three-Dimensional Human Intestinal Organoids as a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of Enteroviruses
por: Tsang, Jessica Oi-Ling, et al.
Publicado: (2021)

Antibody-Dependent Cell-Mediated Cytotoxicity Epitopes on the Hemagglutinin Head Region of Pandemic H1N1 Influenza Virus Play Detrimental Roles in H1N1-Infected Mice
por: Ye, Zi-Wei, et al.
Publicado: (2017)

Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters
por: Lee, Andrew Chak-Yiu, et al.
Publicado: (2020)

931. Host PFKFB3-dependent glycolytic reprogramming as a broad-spectrum antiviral strategy
por: Yuan, Shuofeng, et al.
Publicado: (2023)

Pathogenicity of SARS-CoV-2 Omicron BA.1.1 in hamsters
por: Chan, Jasper Fuk-Woo, et al.
Publicado: (2022)

A lethal mouse model using a mouse-adapted SARS-CoV-2 strain with enhanced binding to mouse ACE2 as an important platform for COVID-19 research
por: Chu, Hin, et al.
Publicado: (2021)

Targeting ACLY efficiently inhibits SARS-CoV-2 replication
por: Yuen, Terrence Tsz-Tai, et al.
Publicado: (2022)

918. Identification of novel druggable host targets for Middle East respiratory syndrome coronavirus using a quantitative phosphoproteomics approach
por: Chan, Jasper F W, et al.
Publicado: (2023)

SARS-CoV-2 Induces a More Robust Innate Immune Response and Replicates Less Efficiently Than SARS-CoV in the Human Intestines: An Ex Vivo Study With Implications on Pathogenesis of COVID-19
por: Chu, Hin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7tri9hfofv7h3rrd1ejljip56j