Tick-borne encephalitis virus NS4A ubiquitination antagonizes type I interferon-stimulated STAT1/2 signalling pathway

Tick-borne encephalitis virus (TBEV) accounts for approximately 10,000 annual cases of severe encephalitis in Europe and Asia and causes encephalitis in humans. In this study, we demonstrate TBEV appears to activate the interferon (IFN)-β dependent on RIG-I/MDA5. Both the IFN-β accumulation and the...

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Detalles Bibliográficos
Autores principales: Yang, Qi, You, Jia, Zhou, Yuan, Wang, Yun, Pei, Rongjuan, Chen, Xinwen, Yang, Min, Chen, Jizheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170394/
https://www.ncbi.nlm.nih.gov/pubmed/32196427
http://dx.doi.org/10.1080/22221751.2020.1745094

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