Cargando…

Mouse model of metformin-induced diarrhea

OBJECTIVE: Metformin, an oral medication used for type 2 diabetes mellitus, is the most commonly prescribed drug with less economic burden of patients. Although metformin’s efficacy and safety have long been recognized, approximately 5% of the patients treated with this drug develop severe diarrhea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takemori, Hiroshi, Hamamoto, Akie, Isogawa, Kenta, Ito, Masafumi, Takagi, Masanori, Morino, Hirofumi, Miura, Takanori, Oshida, Kyoichi, Shibata, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170402/ https://www.ncbi.nlm.nih.gov/pubmed/32213489 http://dx.doi.org/10.1136/bmjdrc-2019-000898

Ejemplares similares

Effect of extremely low-concentration gaseous chlorine dioxide against surface Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii in wet conditions on glass dishes
por: Morino, Hirofumi, et al.
Publicado: (2020)

Role of KLF15 in Regulation of Hepatic Gluconeogenesis and Metformin Action
por: Takashima, Mototsugu, et al.
Publicado: (2010)

Six-month low level chlorine dioxide gas inhalation toxicity study with two-week recovery period in rats
por: Akamatsu, Akinori, et al.
Publicado: (2012)

Metformin Treatment May Increase Omentin-1 Levels in Women With Polycystic Ovary Syndrome
por: Tan, Bee K., et al.
Publicado: (2010)

Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation
por: Moonira, Tabassum, et al.
Publicado: (2020)

Protein Tyrosine Phosphatase 1B Deficiency Improves Glucose Homeostasis in Type 1 Diabetes Treated With Leptin
por: Ito, Yoshihiro, et al.
Publicado: (2022)

The High Content of Ent-11α-hydroxy-15-oxo-kaur- 16-en-19-oic Acid in Adenostemma lavenia (L.) O. Kuntze Leaf Extract: With Preliminary in Vivo Assays
por: Hamamoto, Akie, et al.
Publicado: (2020)

Potential Ketoacidosis Linked to Imeglimin and Metformin Co-administration in a Patient With Type 2 Diabetes
por: Yamagishi, Hirofumi, et al.
Publicado: (2023)

Role of DNA Methylation in the Regulation of Lipogenic Glycerol-3-Phosphate Acyltransferase 1 Gene Expression in the Mouse Neonatal Liver
por: Ehara, Tatsuya, et al.
Publicado: (2012)

The Antiaging Effect of Active Fractions and Ent-11α-Hydroxy-15-Oxo-Kaur-16-En-19-Oic Acid Isolated from Adenostemma lavenia (L.) O. Kuntze at the Cellular Level
por: Batubara, Irmanida, et al.
Publicado: (2020)

Shape of the OGTT glucose response curve: relationship with β-cell function and differences by sex, race, and BMI in adults with early type 2 diabetes treated with metformin
por: Utzschneider, Kristina M, et al.
Publicado: (2021)

Successful Resolution of Glucose Toxicity With the Use of Fixed-Ratio Combination Injection of Basal Insulin and Short-Acting Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist
por: Miura, Hiroshi, et al.
Publicado: (2022)

Metformin Use and Metformin-associated Lactic Acidosis in Intensive Care Unit Patients with Diabetes
por: Rajasurya, Venkat, et al.
Publicado: (2019)

Total energy expenditure is comparable between patients with and without diabetes mellitus: Clinical Evaluation of Energy Requirements in Patients with Diabetes Mellitus (CLEVER-DM) Study
por: Morino, Katsutaro, et al.
Publicado: (2019)

Metformin-Induced Acute Hepatitis
por: Mian, Arooj, et al.
Publicado: (2023)

Differences in the Intestinal Microbiome Associated with Diarrhea during Lenvatinib Treatment for Hepatocellular Carcinoma
por: Inukai, Yosuke, et al.
Publicado: (2023)

l-Tryptophan-mediated Enhancement of Susceptibility to Nonalcoholic Fatty Liver Disease Is Dependent on the Mammalian Target of Rapamycin
por: Osawa, Yosuke, et al.
Publicado: (2011)

Metformin-associated Lactic Acidosis: An Unexpected Scenario
por: Asif, Samia, et al.
Publicado: (2019)

The Future of Metformin in the Prevention of Diabetes-Related Osteoporosis
por: Aung, Myat, et al.
Publicado: (2020)

A Case of Metformin-Associated Lactic Acidosis
por: Mahmood, Rabia, et al.
Publicado: (2023)

Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance
por: Kawano, Yoshinaga, et al.
Publicado: (2012)

Myostatin Inhibition Prevents Diabetes and Hyperphagia in a Mouse Model of Lipodystrophy
por: Guo, Tingqing, et al.
Publicado: (2012)

Reactive Hypoglycemia From Metformin Immediate-Release Monotherapy Resolved by a Switch to Metformin Extended-Release: Conceptualizing Their Concentration-Time Curves
por: Akram, Ayesha
Publicado: (2021)

Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity
por: Prawitt, Janne, et al.
Publicado: (2011)

Hepatic Glucagon Action Is Essential for Exercise-Induced Reversal of Mouse Fatty Liver
por: Berglund, Eric D., et al.
Publicado: (2011)

Metformin-Induced Lactic Acidosis: A Case Study
por: Chowdhury, Waliul, et al.
Publicado: (2018)

A Case Report on Metformin-Associated Lactic Acidosis
por: Rai, Harpreet K, et al.
Publicado: (2020)

Synergistic Inhibitory Effects of Hypoxia and Iron Deficiency on Hepatic Glucose Response in Mouse Liver
por: Nam, Hyeyoung, et al.
Publicado: (2016)

GLUT4 Is Not Necessary for Overload-Induced Glucose Uptake or Hypertrophic Growth in Mouse Skeletal Muscle
por: McMillin, Shawna L., et al.
Publicado: (2017)

Sucrase-Isomaltase Deficiency Causing Persistent Bloating and Diarrhea in an Adult Female
por: Chiruvella, Varsha, et al.
Publicado: (2021)

Metformin-Associated Lactic Acidosis: A Case Report and Review
por: Ashraf, Shoaib, et al.
Publicado: (2022)

LBODP034 Metformin Associated Lactic Acidosis, Rare But Real
por: Khalifa, Maram, et al.
Publicado: (2022)

SAT136 Severe Lactic Acidosis Due To Metformin Use.
por: Khan, Areej
Publicado: (2023)

First characterization of glucose flux through the hexosamine biosynthesis pathway (HBP) in ex vivo mouse heart
por: Olson, Aaron K., et al.
Publicado: (2020)

Urinary excretion of B-group vitamins reflects the nutritional status of B-group vitamins in rats
por: Shibata, Katsumi, et al.
Publicado: (2013)

OR01-2 Increased Fracture Risk in Patients Using Insulin Compared to Metformin, Attenuated in Patients Using Combination of Insulin and Metformin: Based on Common Data Models
por: Kim, Kwangsoo, et al.
Publicado: (2022)

Adiponectin Upregulates Ferritin Heavy Chain in Skeletal Muscle Cells
por: Ikegami, Yuichi, et al.
Publicado: (2009)

Vasoactive Intestinal Peptide Tumor as the Cause of Persistent Diarrhea: A Diagnostic Challenge
por: Lopes, Sara, et al.
Publicado: (2022)

Targeted Loss of GHR Signaling in Mouse Skeletal Muscle Protects Against High-Fat Diet–Induced Metabolic Deterioration
por: Vijayakumar, Archana, et al.
Publicado: (2012)

Tissue-Specific Inactivation of Type 2 Deiodinase Reveals Multilevel Control of Fatty Acid Oxidation by Thyroid Hormone in the Mouse
por: Fonseca, Tatiana L., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_d17mmi7vi96meboqni29c0iorp