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Efficacy and safety of linaclotide for opioid-induced constipation in patients with chronic noncancer pain syndromes from a phase 2 randomized study

Constipation is the most common adverse event (AE) of opioid therapy. This multicenter, phase 2 study evaluated the efficacy and safety of linaclotide in treating opioid-induced constipation (OIC) in patients with chronic noncancer pain syndromes (NCT02270983). Adults with OIC (<3 spontaneous bow...

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Detalles Bibliográficos
Autores principales:	Brenner, Darren M., Argoff, Charles E., Fox, Susan M., Bochenek, Wieslaw, D'Astoli, Patricia, Blakesley, Rick E., Reasner, David S., O'Dea, Christopher R., Cash, Brooks D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170446/ https://www.ncbi.nlm.nih.gov/pubmed/32310620 http://dx.doi.org/10.1097/j.pain.0000000000001754

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