Gene expression dynamic analysis reveals co-activation of Sonic Hedgehog and epidermal growth factor followed by dynamic silencing

Aberrant activation of the Sonic Hedgehog (SHH) gene is observed in various cancers. Previous studies have shown a “cross-talk” effect between the canonical Hedgehog signaling pathway and the Epidermal Growth Factor (EGF) pathway when SHH is active in the presence of EGF. However, the precise mechan...

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Detalles Bibliográficos
Autores principales: Maroufy, Vahed, Shah, Pankil, Asghari, Arvand, Deng, Nan, Le, Rosemarie N.U., Ramirez, Juan C., Yaseen, Ashraf, Zheng, W. Jim, Umetani, Michihisa, Wu, Hulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170495/
https://www.ncbi.nlm.nih.gov/pubmed/32341755
http://dx.doi.org/10.18632/oncotarget.27547

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