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Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer

Introduction: Oncogenic activation of ERG resulting from TMPRSS2-ERG gene fusion is a key molecular genetic alteration in prostate cancer (CaP). The frequency of ERG fusion is variable by race; however, there are limited data available on germline polymorphisms associating with ERG fusion status. Th...

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Detalles Bibliográficos
Autores principales: Kohaar, Indu, Li, Qiyuan, Chen, Yongmei, Ravindranath, Lakshmi, Young, Denise, Ali, Amina, Sesterhenn, Isabell A., Rosner, Inger L., Cullen, Jennifer, Srivastava, Shiv, Freedman, Matthew, Petrovics, Gyorgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170497/
https://www.ncbi.nlm.nih.gov/pubmed/32341752
http://dx.doi.org/10.18632/oncotarget.27534