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Targeted alpha therapy using astatine ((211)At)-labeled phenylalanine: A preclinical study in glioma bearing mice
Phenylalanine derivatives, which target tumors especially through L-type amino acid transporter-1 (LAT1), have elicited considerable attention. In this study, we evaluated the treatment effect of phenylalanine labeled with the alpha emitter astatine ((211)At-PA) in tumor bearing mice. The C6 glioma,...
Autores principales: | Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Liu, Yuwei, Ooe, Kazuhiro, Teramoto, Takahiro, Toyoshima, Atsushi, Shimosegawa, Eku, Nakano, Takashi, Kanai, Yoshikatsu, Shinohara, Atsushi, Hatazawa, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170498/ https://www.ncbi.nlm.nih.gov/pubmed/32341757 http://dx.doi.org/10.18632/oncotarget.27552 |
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