Multicomponent diffusion analysis reveals microstructural alterations in spinal cord of a mouse model of amyotrophic lateral sclerosis ex vivo

The microstructure changes associated with degeneration of spinal axons in amyotrophic lateral sclerosis (ALS) may be reflected in altered water diffusion properties, potentially detectable with diffusion-weighted (DW) MRI. Prior work revealed the classical mono-exponential model fails to precisely...

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Detalles Bibliográficos
Autores principales: Gao, Jin, Jiang, Mingchen, Magin, Richard L., Gatto, Rodolfo G., Morfini, Gerardo, Larson, Andrew C., Li, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170503/
https://www.ncbi.nlm.nih.gov/pubmed/32310954
http://dx.doi.org/10.1371/journal.pone.0231598

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