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γ-Hydroxybutyrate does not mediate glucose inhibition of glucagon secretion

Hypersecretion of glucagon from pancreatic α-cells strongly contributes to diabetic hyperglycemia. Moreover, failure of α-cells to increase glucagon secretion in response to falling blood glucose concentrations compromises the defense against hypoglycemia, a common complication in diabetes therapy....

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Detalles Bibliográficos
Autores principales:	Yu, Qian, Lai, Bao Khanh, Ahooghalandari, Parvin, Helander, Anders, Gylfe, Erik, Gilon, Patrick, Tengholm, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170508/ https://www.ncbi.nlm.nih.gov/pubmed/32156704 http://dx.doi.org/10.1074/jbc.RA119.009577

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