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KIT ligand protects against both light-induced and genetic photoreceptor degeneration

Photoreceptor degeneration is a major cause of blindness and a considerable health burden during aging but effective therapeutic or preventive strategies have not so far become readily available. Here, we show in mouse models that signaling through the tyrosine kinase receptor KIT protects photorece...

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Detalles Bibliográficos
Autores principales: Li, Huirong, Lian, Lili, Liu, Bo, Chen, Yu, Yang, Jinglei, Jian, Shuhui, Zhou, Jiajia, Xu, Ying, Ma, Xiaoyin, Qu, Jia, Hou, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170656/
https://www.ncbi.nlm.nih.gov/pubmed/32242818
http://dx.doi.org/10.7554/eLife.51698