Pan‐tissue analysis of allelic alternative polyadenylation suggests widespread functional regulation

Alternative polyadenylation (APA) is a major layer of gene regulation. However, it has recently been argued that most APA represents molecular noise. To clarify their functional relevance and evolution, we quantified allele‐specific APA patterns in multiple tissues from an F1 hybrid mouse. We found...

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Detalles Bibliográficos
Autores principales: Li, Yisheng, Schaefke, Bernhard, Zou, Xudong, Zhang, Min, Heyd, Florian, Sun, Wei, Zhang, Bin, Li, Guipeng, Liang, Weizheng, He, Yuhao, Zhou, Juexiao, Li, Yunfei, Fang, Liang, Hu, Yuhui, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170663/
https://www.ncbi.nlm.nih.gov/pubmed/32311237
http://dx.doi.org/10.15252/msb.20199367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170663/
https://www.ncbi.nlm.nih.gov/pubmed/32311237
http://dx.doi.org/10.15252/msb.20199367

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