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The ABC exporter IrtAB imports and reduces mycobacterial siderophores
Intracellular replication of the deadly pathogen Mycobacterium tuberculosis relies on the production of small organic molecules called siderophores to scavenge iron from host proteins(1). M. tuberculosis produces two classes of siderophores, lipid-bound mycobactin and soluble carboxymycobactin(2, 3)...
Autores principales: | Arnold, Fabian M., Weber, Miriam S., Gonda, Imre, Gallenito, Marc J., Adenau, Sophia, Egloff, Pascal, Zimmermann, Iwan, Hutter, Cedric A.J., Hürlimann, Lea M., Peters, Eike, Piel, Jörn, Meloni, Gabriele, Medalia, Ohad, Seeger, Markus A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170716/ https://www.ncbi.nlm.nih.gov/pubmed/32296173 http://dx.doi.org/10.1038/s41586-020-2136-9 |
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