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Analysis of the impact of diagnostic virology tests on the use of antibiotics in paediatric inpatients with community-acquired pneumonia()

INTRODUCTION: Viruses are one of the most common causes of community-acquired pneumonia (CAP) in children. Early identification of respiratory viruses could result in a decrease in the use of antibiotics. METHODS: Observational, retrospective study from January 2014 to June 2018, that included paedi...

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Autores principales: Aguilera-Alonso, David, Illán-Ramos, Marta, Daoud, Zarife, Guinea, Víctor, Culebras, Esther, Ramos, José Tomás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170796/
http://dx.doi.org/10.1016/j.eimce.2019.08.005
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author Aguilera-Alonso, David
Illán-Ramos, Marta
Daoud, Zarife
Guinea, Víctor
Culebras, Esther
Ramos, José Tomás
author_facet Aguilera-Alonso, David
Illán-Ramos, Marta
Daoud, Zarife
Guinea, Víctor
Culebras, Esther
Ramos, José Tomás
author_sort Aguilera-Alonso, David
collection PubMed
description INTRODUCTION: Viruses are one of the most common causes of community-acquired pneumonia (CAP) in children. Early identification of respiratory viruses could result in a decrease in the use of antibiotics. METHODS: Observational, retrospective study from January 2014 to June 2018, that included paediatric patients admitted with a diagnosis of CAP in a tertiary hospital, in which antigenic tests and/or viral PCR on a respiratory sample was performed. RESULTS: A total of 105 CAP episodes were included, with identification of a respiratory virus in 93 (88.6%) cases. Patients with respiratory syncytial virus (RSV) detection had a lower onset of empirical antibiotic therapy (35.1% vs. 55.9%, p-value = .042). In addition, cases with RSV or influenza identification required shorter duration of antibiotic therapy (receiving 45.6% ≥2 days vs. 68.8% of those not identified, p = .017). CONCLUSION: The use of respiratory virus diagnostic techniques in our setting can optimise antibiotic use in children admitted with CAP.
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spelling pubmed-71707962020-04-21 Analysis of the impact of diagnostic virology tests on the use of antibiotics in paediatric inpatients with community-acquired pneumonia() Aguilera-Alonso, David Illán-Ramos, Marta Daoud, Zarife Guinea, Víctor Culebras, Esther Ramos, José Tomás Enfermedades infecciosas y microbiologia clinica (English ed.) Article INTRODUCTION: Viruses are one of the most common causes of community-acquired pneumonia (CAP) in children. Early identification of respiratory viruses could result in a decrease in the use of antibiotics. METHODS: Observational, retrospective study from January 2014 to June 2018, that included paediatric patients admitted with a diagnosis of CAP in a tertiary hospital, in which antigenic tests and/or viral PCR on a respiratory sample was performed. RESULTS: A total of 105 CAP episodes were included, with identification of a respiratory virus in 93 (88.6%) cases. Patients with respiratory syncytial virus (RSV) detection had a lower onset of empirical antibiotic therapy (35.1% vs. 55.9%, p-value = .042). In addition, cases with RSV or influenza identification required shorter duration of antibiotic therapy (receiving 45.6% ≥2 days vs. 68.8% of those not identified, p = .017). CONCLUSION: The use of respiratory virus diagnostic techniques in our setting can optimise antibiotic use in children admitted with CAP. Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. 2020-05 2020-04-21 /pmc/articles/PMC7170796/ http://dx.doi.org/10.1016/j.eimce.2019.08.005 Text en © 2019 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Aguilera-Alonso, David
Illán-Ramos, Marta
Daoud, Zarife
Guinea, Víctor
Culebras, Esther
Ramos, José Tomás
Analysis of the impact of diagnostic virology tests on the use of antibiotics in paediatric inpatients with community-acquired pneumonia()
title Analysis of the impact of diagnostic virology tests on the use of antibiotics in paediatric inpatients with community-acquired pneumonia()
title_full Analysis of the impact of diagnostic virology tests on the use of antibiotics in paediatric inpatients with community-acquired pneumonia()
title_fullStr Analysis of the impact of diagnostic virology tests on the use of antibiotics in paediatric inpatients with community-acquired pneumonia()
title_full_unstemmed Analysis of the impact of diagnostic virology tests on the use of antibiotics in paediatric inpatients with community-acquired pneumonia()
title_short Analysis of the impact of diagnostic virology tests on the use of antibiotics in paediatric inpatients with community-acquired pneumonia()
title_sort analysis of the impact of diagnostic virology tests on the use of antibiotics in paediatric inpatients with community-acquired pneumonia()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170796/
http://dx.doi.org/10.1016/j.eimce.2019.08.005
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