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Comparative Pro-cognitive and Neurochemical Profiles of Glycine Modulatory Site Agonists and Glycine Reuptake Inhibitors in the Rat: Potential Relevance to Cognitive Dysfunction and Its Management

Frontocortical NMDA receptors are pivotal in regulating cognition and mood, are hypofunctional in schizophrenia, and may contribute to autistic spectrum disorders. Despite extensive interest in agents potentiating activity at the co-agonist glycine modulatory site, few comparative functional studies...

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Detalles Bibliográficos
Autores principales: Fone, Kevin C.F., Watson, David J.G., Billiras, Rodolphe I., Sicard, Dorothee I., Dekeyne, Anne, Rivet, Jean-Michel, Gobert, Alain, Millan, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170834/
https://www.ncbi.nlm.nih.gov/pubmed/31960362
http://dx.doi.org/10.1007/s12035-020-01875-9