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Comparative Pro-cognitive and Neurochemical Profiles of Glycine Modulatory Site Agonists and Glycine Reuptake Inhibitors in the Rat: Potential Relevance to Cognitive Dysfunction and Its Management
Frontocortical NMDA receptors are pivotal in regulating cognition and mood, are hypofunctional in schizophrenia, and may contribute to autistic spectrum disorders. Despite extensive interest in agents potentiating activity at the co-agonist glycine modulatory site, few comparative functional studies...
Autores principales: | Fone, Kevin C.F., Watson, David J.G., Billiras, Rodolphe I., Sicard, Dorothee I., Dekeyne, Anne, Rivet, Jean-Michel, Gobert, Alain, Millan, Mark J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170834/ https://www.ncbi.nlm.nih.gov/pubmed/31960362 http://dx.doi.org/10.1007/s12035-020-01875-9 |
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