Sepiapterin reductase promotes hepatocellular carcinoma progression via FoxO3a/Bim signaling in a nonenzymatic manner

Sepiapterin reductase plays an enzymatic role in the biosynthesis of tetrahydrobiopterin, which is reported in limited studies to regulate the progression of several tumors. However, the role of sepiapterin reductase in hepatocellular carcinoma remains largely unknown. Here, we found that sepiapteri...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yao, Du, Hongzhi, Zhan, Meixiao, Wang, Hongxv, Chen, Peng, Du, Danyu, Liu, Xinyi, Huang, Xingxv, Ma, Pengcheng, Peng, Dezheng, Sun, Li, Yuan, Shengtao, Ding, Jian, Lu, Ligong, Jiang, Jingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170898/
https://www.ncbi.nlm.nih.gov/pubmed/32312975
http://dx.doi.org/10.1038/s41419-020-2471-7

Ejemplares similares

Ejemplares similares