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Determining organ weight toxicity with Bayesian causal models: Improving on the analysis of relative organ weights
Regulatory authorities require animal toxicity tests for new chemical entities. Organ weight changes are accepted as a sensitive indicator of chemically induced organ damage, but can be difficult to interpret because changes in organ weight might reflect chemically-induced changes in overall body we...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170916/ https://www.ncbi.nlm.nih.gov/pubmed/32313041 http://dx.doi.org/10.1038/s41598-020-63465-y |