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The non-receptor tyrosine kinase Pyk2 modulates acute locomotor effects of cocaine in D1 receptor-expressing neurons of the nucleus accumbens
The striatum is critical for cocaine-induced locomotor responses. Although the role of D1 receptor-expressing neurons is established, underlying molecular pathways are not fully understood. We studied the role of Pyk2, a non-receptor, calcium-dependent protein-tyrosine kinase. The locomotor coordina...
Autores principales: | de Pins, Benoit, Montalban, Enrica, Vanhoutte, Peter, Giralt, Albert, Girault, Jean-Antoine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170924/ https://www.ncbi.nlm.nih.gov/pubmed/32313025 http://dx.doi.org/10.1038/s41598-020-63426-5 |
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