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Epigenetics and Mitochondrial Stability in the Metabolic Memory Phenomenon Associated with Continued Progression of Diabetic Retinopathy
Retinopathy continues to progress even when diabetic patients try to control their blood sugar, but the molecular mechanism of this ‘metabolic memory’ phenomenon remains elusive. Retinal mitochondria remain damaged and vicious cycle of free radicals continues to self-propagate. DNA methylation suppr...
Autores principales: | Kowluru, Renu A., Mohammad, Ghulam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171070/ https://www.ncbi.nlm.nih.gov/pubmed/32313015 http://dx.doi.org/10.1038/s41598-020-63527-1 |
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