Cargando…

Kinesin-7 CENP-E regulates chromosome alignment and genome stability of spermatogenic cells

Kinesin-7 CENP-E is an essential kinetochore motor required for chromosome alignment and congression. However, the specific functions of CENP-E in the spermatogenic cells during spermatogenesis remain unknown. In this study, we find that CENP-E proteins are expressed in the spermatogonia, spermatocy...

Descripción completa

Detalles Bibliográficos
Autores principales:	She, Zhen-Yu, Yu, Kai-Wei, Zhong, Ning, Xiao, Yu, Wei, Ya-Lan, Lin, Yang, Li, Yue-Ling, Lu, Ming-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171076/ https://www.ncbi.nlm.nih.gov/pubmed/32351712 http://dx.doi.org/10.1038/s41420-020-0261-8

Ejemplares similares

Kinesin-5 Eg5 is essential for spindle assembly and chromosome alignment of mouse spermatocytes
por: She, Zhen-Yu, et al.
Publicado: (2020)

CENP-meta, an Essential Kinetochore Kinesin Required for the Maintenance of Metaphase Chromosome Alignment in Drosophila
por: Yucel, Jennifer K., et al.
Publicado: (2000)

Kinesin-5 Eg5 is essential for spindle assembly, chromosome stability and organogenesis in development
por: Yu, Wen-Xin, et al.
Publicado: (2022)

CENP-E Function at Kinetochores Is Essential for Chromosome Alignment
por: Schaar, B.T., et al.
Publicado: (1997)

Lateral to End-on Conversion of Chromosome-Microtubule Attachment Requires Kinesins CENP-E and MCAK
por: Shrestha, Roshan L., et al.
Publicado: (2013)

Lateral to End-on Conversion of Chromosome-Microtubule Attachment Requires Kinesins CENP-E and MCAK
por: Shrestha, Roshan L., et al.
Publicado: (2013)

SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores
por: Li, Teng, et al.
Publicado: (2016)

LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochores
por: Wu, Min, et al.
Publicado: (2019)

Leaving no-one behind: how CENP-E facilitates chromosome alignment
por: Craske, Benjamin, et al.
Publicado: (2020)

Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro
Publicado: (1995)

CENP-V is required for centromere organization, chromosome alignment and cytokinesis
por: Tadeu, Ana Mafalda Baptista, et al.
Publicado: (2008)

Kinesin-like protein CENP-E is upregulated in rheumatoid synovial fibroblasts
por: Kullmann , Frank, et al.
Publicado: (1999)

Chromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways
por: Bancroft, James, et al.
Publicado: (2015)

HPV16 E6 induces chromosomal instability due to polar chromosomes caused by E6AP-dependent degradation of the mitotic kinesin CENP-E
por: Cosper, Pippa F., et al.
Publicado: (2023)

CENP-E–dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint
por: Guo, Yige, et al.
Publicado: (2012)

The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment
por: Legal, Thibault, et al.
Publicado: (2020)

Kinetochore–microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E
por: Vitre, Benjamin, et al.
Publicado: (2014)

Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips
por: Gudimchuk, Nikita, et al.
Publicado: (2013)

Structural analysis of fungal CENP-H/I/K homologs reveals a conserved assembly mechanism underlying proper chromosome alignment
por: Hu, Liqiao, et al.
Publicado: (2019)

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores
por: Ditchfield, Claire, et al.
Publicado: (2003)

A unique kinesin-8 surface loop provides specificity for chromosome alignment
por: Kim, Haein, et al.
Publicado: (2014)

TRAMM/TrappC12 plays a role in chromosome congression, kinetochore stability, and CENP-E recruitment
por: Milev, Miroslav P., et al.
Publicado: (2015)

Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast
por: Au, Wei-Chun, et al.
Publicado: (2020)

Evaluating the Relationship between Spermatogenic Silencing of the X Chromosome and Evolution of the Y Chromosome in Chimpanzee and Human
por: Mulugeta Achame, Eskeatnaf, et al.
Publicado: (2010)

Does FANCA Assist CENP-E in Architectural Organization of Chromosomes at Spindle Equator?
por: El-Arabey, Amr Ahmed, et al.
Publicado: (2018)

Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes
por: Topper, Leana M., et al.
Publicado: (2001)

CENP-A Ubiquitylation Contributes to Maintaining the Chromosomal Location of the Centromere
por: Niikura, Yohei, et al.
Publicado: (2019)

CENP-A and topoisomerase-II antagonistically affect chromosome length
por: Ladouceur, A.-M., et al.
Publicado: (2017)

Immunization with CENP-C Causes Aberrant Chromosome Segregation during Oocyte Meiosis in Mice
por: Fan, Jiao, et al.
Publicado: (2021)

Changes in Expressions of Spermatogenic Marker Genes and Spermatogenic Cell Population Caused by Stress
por: Tian, Pengxiang, et al.
Publicado: (2021)

Relative safety of various spermatogenic stem cell purification methods for application in spermatogenic stem cell transplantation
por: Tian, Jia, et al.
Publicado: (2019)

BUB-1 and CENP-C recruit PLK-1 to control chromosome alignment and segregation during meiosis I in C. elegans oocytes
por: Taylor, Samuel JP, et al.
Publicado: (2023)

CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly
por: Shono, Nobuaki, et al.
Publicado: (2015)

Impaired CENP-E Function Renders Large Chromosomes More Vulnerable to Congression Failure
por: Tovini, Laura, et al.
Publicado: (2019)

Novel IFT140 variants cause spermatogenic dysfunction in humans
por: Wang, Xiong, et al.
Publicado: (2019)

Exposure to Silica Nanoparticles Causes Reversible Damage of the Spermatogenic Process in Mice
por: Xu, Ying, et al.
Publicado: (2014)

CENP-E falls off
por: Wells, William A.
Publicado: (2001)

Bioinformatic identification of key genes and molecular pathways in the spermatogenic process of cryptorchidism
por: Zhou, Yu, et al.
Publicado: (2018)

The histone H3/H4 chaperone CHAF1B prevents the mislocalization of CENP-A for chromosomal stability
por: Shrestha, Roshan L., et al.
Publicado: (2023)

Molecular basis of CENP-C association with the CENP-A nucleosome at yeast centromeres
por: Xiao, Hua, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_8j3lh45conov2lfruo7d2b30r4