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Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived eXplant model

Transformation of castration-resistant prostate cancer (CRPC) into an aggressive neuroendocrine disease (CRPC-NE) represents a major clinical challenge and experimental models are lacking. A CTC-derived eXplant (CDX) and a CDX-derived cell line are established using circulating tumor cells (CTCs) ob...

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Detalles Bibliográficos
Autores principales: Faugeroux, Vincent, Pailler, Emma, Oulhen, Marianne, Deas, Olivier, Brulle-Soumare, Laura, Hervieu, Céline, Marty, Virginie, Alexandrova, Kamelia, Andree, Kiki C., Stoecklein, Nikolas H., Tramalloni, Dominique, Cairo, Stefano, NgoCamus, Maud, Nicotra, Claudio, Terstappen, Leon W. M. M., Manaresi, Nicolo, Lapierre, Valérie, Fizazi, Karim, Scoazec, Jean-Yves, Loriot, Yohann, Judde, Jean-Gabriel, Farace, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171138/
https://www.ncbi.nlm.nih.gov/pubmed/32313004
http://dx.doi.org/10.1038/s41467-020-15426-2