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Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis
Genomic DNA is folded into a higher-order structure that regulates transcription and maintains genomic stability. Although progress has been made on understanding biochemical characteristics of epigenetic modifications in cancer, the in-situ higher-order folding of chromatin structure during maligna...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171144/ https://www.ncbi.nlm.nih.gov/pubmed/32313005 http://dx.doi.org/10.1038/s41467-020-15718-7 |