Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis

Genomic DNA is folded into a higher-order structure that regulates transcription and maintains genomic stability. Although progress has been made on understanding biochemical characteristics of epigenetic modifications in cancer, the in-situ higher-order folding of chromatin structure during maligna...

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Detalles Bibliográficos
Autores principales: Xu, Jianquan, Ma, Hongqiang, Ma, Hongbin, Jiang, Wei, Mela, Christopher A., Duan, Meihan, Zhao, Shimei, Gao, Chenxi, Hahm, Eun-Ryeong, Lardo, Santana M., Troy, Kris, Sun, Ming, Pai, Reet, Stolz, Donna B., Zhang, Lin, Singh, Shivendra, Brand, Randall E., Hartman, Douglas J., Hu, Jing, Hainer, Sarah J., Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171144/
https://www.ncbi.nlm.nih.gov/pubmed/32313005
http://dx.doi.org/10.1038/s41467-020-15718-7

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