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Molecular profiling of driver events in metastatic uveal melanoma

Metastatic uveal melanoma is less well understood than its primary counterpart, has a distinct biology compared to skin melanoma, and lacks effective treatments. Here we genomically profile metastatic tumors and infiltrating lymphocytes. BAP1 alterations are overrepresented and found in 29/32 of cas...

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Detalles Bibliográficos
Autores principales:	Karlsson, Joakim, Nilsson, Lisa M., Mitra, Suman, Alsén, Samuel, Shelke, Ganesh Vilas, Sah, Vasu R., Forsberg, Elin M. V., Stierner, Ulrika, All-Eriksson, Charlotta, Einarsdottir, Berglind, Jespersen, Henrik, Ny, Lars, Lindnér, Per, Larsson, Erik, Olofsson Bagge, Roger, Nilsson, Jonas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171146/ https://www.ncbi.nlm.nih.gov/pubmed/32313009 http://dx.doi.org/10.1038/s41467-020-15606-0

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