P53 suppresses SENP3 phosphorylation to mediate G2 checkpoint

In response to DNA damage, p53-mediated signaling is regulated by protein phosphorylation and ubiquitination to precisely control G2 checkpoint. Here we demonstrated that protein SUMOylation also engaged in regulation of p53-mediated G2 checkpoint. We found that G2 DNA damage suppressed SENP3 phosph...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Tian, Jing, Huang, Chao, Ma, Jiao, Hu, Gaolei, Chen, Yalan, Wang, Tianshi, Cai, Rong, Zuo, Yong, Tan, Hongsheng, Fan, Qiuju, Dong, Baijun, Xue, Wei, Yi, Jing, Chen, Guoqiang, Tu, Jun, Cheng, Jinke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171148/
https://www.ncbi.nlm.nih.gov/pubmed/32351703
http://dx.doi.org/10.1038/s41421-020-0154-2

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