α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease

A diagnosis of motor Parkinson’s disease (PD) is preceded by a prolonged premotor phase with accumulating neuronal damage. Here we examined the temporal relation between α-synuclein (α-syn) T cell reactivity and PD. A longitudinal case study revealed that elevated α-syn-specific T cell responses wer...

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Detalles Bibliográficos
Autores principales: Lindestam Arlehamn, Cecilia S., Dhanwani, Rekha, Pham, John, Kuan, Rebecca, Frazier, April, Rezende Dutra, Juliana, Phillips, Elizabeth, Mallal, Simon, Roederer, Mario, Marder, Karen S., Amara, Amy W., Standaert, David G., Goldman, Jennifer G., Litvan, Irene, Peters, Bjoern, Sulzer, David, Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171193/
https://www.ncbi.nlm.nih.gov/pubmed/32313102
http://dx.doi.org/10.1038/s41467-020-15626-w

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