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Reduction of SOST gene promotes bone formation through the Wnt/β‐catenin signalling pathway and compensates particle‐induced osteolysis
The increase in bone resorption and/or the inhibition of bone regeneration caused by wear particles are the main causes of periprosthetic osteolysis. The SOST gene and Sclerostin, a protein synthesized by the SOST gene, are the characteristic marker of osteocytes and regulate bone formation and reso...
Autores principales: | Zhang, Zai Hang, Jia, Xin Yu, Fang, Jing Yi, Chai, Hao, Huang, Qun, She, Chang, Jia, Peng, Geng, De Chun, Xu, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171346/ https://www.ncbi.nlm.nih.gov/pubmed/32134561 http://dx.doi.org/10.1111/jcmm.15084 |
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