Cargando…

iNOS‐inhibitor driven neuroprotection in a porcine retina organ culture model

Nitrite oxide plays an important role in the pathogenesis of various retinal diseases, especially when hypoxic processes are involved. This degeneration can be simulated by incubating porcine retinal explants with CoCl(2). Here, the therapeutic potential of iNOS‐inhibitor 1400W was evaluated. Degene...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hurst, José, Mueller‐Buehl, Ana Maria, Hofmann, Lisa, Kuehn, Sandra, Herms, Fenja, Schnichels, Sven, Joachim, Stephanie Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171393/ https://www.ncbi.nlm.nih.gov/pubmed/32130787 http://dx.doi.org/10.1111/jcmm.15091

Ejemplares similares

Reduced Retinal Degeneration in an Oxidative Stress Organ Culture Model through an iNOS-Inhibitor
por: Mueller-Buehl, Ana M., et al.
Publicado: (2021)

Diminished apoptosis in hypoxic porcine retina explant cultures through hypothermia
por: Maliha, Ana M., et al.
Publicado: (2019)

Novel Porcine Retina Cultivation Techniques Provide Improved Photoreceptor Preservation
por: Wagner, Natalie, et al.
Publicado: (2020)

Protective effect of the extremolytes ectoine and hydroxyectoine in a porcine organ culture
por: Tsai, Teresa, et al.
Publicado: (2020)

Establishment of a primary porcine retinal pigment epithelium monolayer to complement retinal ex vivo cultures
por: Fietz, Agnes, et al.
Publicado: (2023)

Correction to: Protective effect of the extremolytes ectoine and hydroxyectoine in a porcine organ culture
por: Tsai, Teresa, et al.
Publicado: (2021)

Editorial: Brain vs. retina - Differences and commonalities: The role of oxidative stress in neurodegenerative diseases
por: Hurst, José, et al.
Publicado: (2023)

Expression of Inducible Nitric Oxide Synthase (iNOS) in Microglia of the Developing Quail Retina
por: Sierra, Ana, et al.
Publicado: (2014)

Effect of iNOS inhibition on exhaled NO and serum nitrate in hyperdynamic porcine endotoxemia
por: Theisen, MM, et al.
Publicado: (2000)

Obesity-Induced Coronary Microvascular Disease Is Prevented by iNOS Deletion and Reversed by iNOS Inhibition
por: Shah, Soham A., et al.
Publicado: (2023)

The dual role of iNOS in cancer()
por: Vannini, Federica, et al.
Publicado: (2015)

Brain function in iNOS knock out or iNOS inhibited (l-NIL) mice under endotoxic shock
por: Schweighöfer, Hanna, et al.
Publicado: (2014)

Co-cultivation of primary porcine RPE cells and neuroretina induces inflammation: a potential inflammatory AMD-model
por: Fietz, Agnes, et al.
Publicado: (2023)

Organ Cultures for Retinal Diseases
por: Hurst, José, et al.
Publicado: (2020)

The expressions of AMACR and iNOS in prostate adenocarcinomas
por: Ozgur, Tumay, et al.
Publicado: (2013)

Targeting iNOS to increase efficacy of immunotherapies
por: Ekmekcioglu, Suhendan, et al.
Publicado: (2017)

Endothelial and coagulation dysfunction during porcine bacteremia: effects of combining iNOS inhibitor and radical scavenger
por: Matejovic, M, et al.
Publicado: (2006)

Discovery of a Natural Product-Like iNOS Inhibitor by Molecular Docking with Potential Neuroprotective Effects In Vivo
por: Zhong, Hai-Jing, et al.
Publicado: (2014)

Upregulation of iNOS and phosphorylated eNOS in the implantation‐induced blastocysts of mice
por: Seki, Misato, et al.
Publicado: (2023)

iNOS polymorphism modulates iNOS/NO expression via impaired antioxidant and ROS content in P. vivax and P. falciparum infection
por: Kumar, Amod, et al.
Publicado: (2017)

Aging and Insulin Resistance: Just Say iNOS
por: Evans, Joseph L., et al.
Publicado: (2013)

Recipient iNOS but Not eNOS Deficiency Reduces Luminal Narrowing in Tracheal Allografts
por: Minamoto, Kanji, et al.
Publicado: (2002)

Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS
por: Morsy, Mohamed A., et al.
Publicado: (2014)

The return of the Scarlet Pimpernel: cobalamin in inflammation II — cobalamins can both selectively promote all three nitric oxide synthases (NOS), particularly iNOS and eNOS, and, as needed, selectively inhibit iNOS and nNOS
por: Wheatley, Carmen
Publicado: (2007)

Impact of Primary RPE Cells in a Porcine Organotypic Co-Cultivation Model
por: Wagner, Natalie, et al.
Publicado: (2022)

Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo
por: Bucci, Mariarosaria, et al.
Publicado: (2013)

eNOS/iNOS and endoplasmic reticulum stress-induced apoptosis in the placentas of patients with preeclampsia
por: Du, L, et al.
Publicado: (2017)

The role of tumour-derived iNOS in tumour progression and angiogenesis
por: Kostourou, V, et al.
Publicado: (2011)

Inhibition of Inflammation and iNOS Improves Lymphatic Function in Obesity
por: Torrisi, Jeremy S., et al.
Publicado: (2016)

Regulation of iNOS on Immune Cells and Its Role in Diseases
por: Xue, Qingjie, et al.
Publicado: (2018)

Hepatic Lysosomal iNOS Activity Impairs Autophagy in Obesity
por: Qian, Qingwen, et al.
Publicado: (2019)

The Potential Role of iNOS in Ovarian Cancer Progression and Chemoresistance
por: Kielbik, Michal, et al.
Publicado: (2019)

Macrophage Reprogramming and Cancer Therapeutics: Role of iNOS-Derived NO
por: Kashfi, Khosrow, et al.
Publicado: (2021)

mRNA expression and localization of bNOS, eNOS and iNOS in human cervix at preterm and term labour
por: Törnblom, Susanne Abelin, et al.
Publicado: (2005)

Porcine Corneas Incubated at Low Humidity Present Characteristic Features Found in Dry Eye Disease
por: Netto, Alice Rocha Teixeira, et al.
Publicado: (2022)

Retraction: Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo
Publicado: (2019)

Two Methods for the Isolation and Cultivation of Porcine Primary Corneal Cells
por: Netto, Alice Rocha Teixeira, et al.
Publicado: (2023)

Design and Synthesis of Imidazopyrimidine Derivatives as Potent iNOS Dimerization Inhibitors
por: Chu, Guo-Hua, et al.
Publicado: (2009)

iNOS expression and osteocyte apoptosis in idiopathic, non-traumatic osteonecrosis
por: Wang, Jun, et al.
Publicado: (2015)

iNOS is associated with tumorigenicity as an independent prognosticator in human intrahepatic cholangiocarcinoma
por: Liu, Sulai, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_h4h0ktcrd76s2sn5mktsi7pr6o