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Transcriptome analyses reveal molecular mechanisms underlying phenotypic differences among transcriptional subtypes of glioblastoma

Using molecular signatures, previous studies have defined glioblastoma (GBM) subtypes with different phenotypes, such as the proneural (PN), neural (NL), mesenchymal (MES) and classical (CL) subtypes. However, the gene programmes underlying the phenotypes of these subtypes were less known. We applie...

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Detalles Bibliográficos
Autores principales: Pan, Yuan‐Bo, Wang, Siqi, Yang, Biao, Jiang, Zhenqi, Lenahan, Cameron, Wang, Jianhua, Zhang, Jianmin, Shao, Anwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171397/
https://www.ncbi.nlm.nih.gov/pubmed/32091665
http://dx.doi.org/10.1111/jcmm.14976