The psoriatic shift induced by interleukin 17 is promptly reverted by a specific anti-IL-17A agent in a three-dimensional organotypic model of normal human skin culture

Interleukin 17A (IL-17A), mainly produced by the T helper subclass Th17, plays a key role in the psoriatic plaque formation and progression. The clinical effectiveness of anti-IL-17A agents is documented, but the early and specific mechanisms of their protection are not identified yet. The challenge...

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Detalles Bibliográficos
Autores principales: Donetti, Elena, Lombardo, Giulia, Indino, Serena, Cornaghi, Laura, Arnaboldi, Francesca, Pescitelli, Leonardo, Baruffaldi Preis, Franz, Prignano, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171424/
https://www.ncbi.nlm.nih.gov/pubmed/32312032
http://dx.doi.org/10.4081/ejh.2020.3115

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