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Wnt-C59 Attenuates Pressure Overload-Induced Cardiac Hypertrophy via Interruption of Wnt Pathway

BACKGROUND: Cardiac hypertrophy usually results in heart failure and is an important cause of mortality worldwide. Wnt/β-catenin signaling pathway hyper-activation is involved in the pathogenesis and progression of cardiac hypertrophy. Wnt-C59 is a small molecular compound, which strongly and specif...

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Detalles Bibliográficos
Autores principales: Zhao, Zhengbo, Liu, Han, Li, Yu, Tian, Jingxiu, Deng, Songbai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171430/
https://www.ncbi.nlm.nih.gov/pubmed/32279067
http://dx.doi.org/10.12659/MSM.923025

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