Prevalence and characteristics of PIK3CA mutation in mismatch repair-deficient colorectal cancer

Background: Chromosomal instability (CIN) and microsatellite instability (MSI) account for the major causes of colorectal cancer (CRC). As an important component of the CIN pathway, PIK3CA mutation is a negative prognostic factor in CRC. However, the relationship between PIK3CA mutation and mismatch...

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Detalles Bibliográficos
Autores principales: Li, Weihua, Qiu, Tian, Dong, Lin, Zhang, Fanshuang, Guo, Lei, Ying, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171509/
https://www.ncbi.nlm.nih.gov/pubmed/32328187
http://dx.doi.org/10.7150/jca.37437

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