Cargando…

Validation of the Turkish version of European Organization for Research and Treatment of Cancer QLQ-OV28 ovarian cancer specific quality of life questionnaire

OBJECTIVE: To examine reliability and validity of the European Organization for Research and Treatment of Cancer (EORTC) QLQ-OV28 questionnaire into the Turkish language according to the instructions provided by EORTC. MATERIALS AND METHODS: Ninety-seven patients who were diagnosed as having ovarian...

Descripción completa

Detalles Bibliográficos
Autores principales: Akdemir, Yeşim, Cam, Çetin, Ay, Nadiye Pınar, Karateke, Ateş
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171542/
https://www.ncbi.nlm.nih.gov/pubmed/32341831
http://dx.doi.org/10.4274/tjod.galenos.2020.26594
_version_ 1783524092175974400
author Akdemir, Yeşim
Cam, Çetin
Ay, Nadiye Pınar
Karateke, Ateş
author_facet Akdemir, Yeşim
Cam, Çetin
Ay, Nadiye Pınar
Karateke, Ateş
author_sort Akdemir, Yeşim
collection PubMed
description OBJECTIVE: To examine reliability and validity of the European Organization for Research and Treatment of Cancer (EORTC) QLQ-OV28 questionnaire into the Turkish language according to the instructions provided by EORTC. MATERIALS AND METHODS: Ninety-seven patients who were diagnosed as having ovarian cancer and treated between January 2005 and June 2010 with an expected survival time of at least 3 months, were enrolled into the study. The exclusion criteria were diagnoses of any disease that could disrupt consciousness and concurrent malignancies. The EORTC QLQ-OV28 module was translated into Turkish by professional translators and physicians. The test–retest reliability of the Turkish version of the questionnaire was performed on 30 patients. Answers were scored according to the instructions provided by the EORTC. The total score was calculated as explained above and after scoring procedures, all subscale scores were linearly transformed to a 0-100 scale. All patients concomitantly completed the Spielberg State Trait Anxiety Inventory (STAI) and Beck Depression Inventory (BDI). Patients were analyzed in two groups: on-treatment and off-treatment groups consisted of patients who did and did not undergo chemotherapy or surgery within the last two months, respectively. The demographic data of all patients were recorded. EORTC QLQ-OV28 scores of both groups were compared. Correlations between EORTC QLQ-OV28 subscales and total score of BDI and STAI were analyzed. RESULTS: For test-retest reliability, Spearman’s rho was 0.84 (p<0.001). The on-treatment group scored statistically significantly higher than the offtreatment group in peripheral neuropathies, attitude to disease and treatment, sexual function and other chemotherapy adverse effect subscales of the questionnaire. Correlations between EORTC QLQ-OV28 subscales and the total scores of BDI and STAI of the groups were statistically significant, except the sexual function subscale. CONCLUSION: The Turkish translated version of EORTC QLQ-OV28 module is a reliable, consistent, and a valid instrument for assessing the impact of treatment modalities on QoL among Turkish speaking women with ovarian cancer.
format Online
Article
Text
id pubmed-7171542
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Galenos Publishing
record_format MEDLINE/PubMed
spelling pubmed-71715422020-04-27 Validation of the Turkish version of European Organization for Research and Treatment of Cancer QLQ-OV28 ovarian cancer specific quality of life questionnaire Akdemir, Yeşim Cam, Çetin Ay, Nadiye Pınar Karateke, Ateş Turk J Obstet Gynecol Clinical Investigation OBJECTIVE: To examine reliability and validity of the European Organization for Research and Treatment of Cancer (EORTC) QLQ-OV28 questionnaire into the Turkish language according to the instructions provided by EORTC. MATERIALS AND METHODS: Ninety-seven patients who were diagnosed as having ovarian cancer and treated between January 2005 and June 2010 with an expected survival time of at least 3 months, were enrolled into the study. The exclusion criteria were diagnoses of any disease that could disrupt consciousness and concurrent malignancies. The EORTC QLQ-OV28 module was translated into Turkish by professional translators and physicians. The test–retest reliability of the Turkish version of the questionnaire was performed on 30 patients. Answers were scored according to the instructions provided by the EORTC. The total score was calculated as explained above and after scoring procedures, all subscale scores were linearly transformed to a 0-100 scale. All patients concomitantly completed the Spielberg State Trait Anxiety Inventory (STAI) and Beck Depression Inventory (BDI). Patients were analyzed in two groups: on-treatment and off-treatment groups consisted of patients who did and did not undergo chemotherapy or surgery within the last two months, respectively. The demographic data of all patients were recorded. EORTC QLQ-OV28 scores of both groups were compared. Correlations between EORTC QLQ-OV28 subscales and total score of BDI and STAI were analyzed. RESULTS: For test-retest reliability, Spearman’s rho was 0.84 (p<0.001). The on-treatment group scored statistically significantly higher than the offtreatment group in peripheral neuropathies, attitude to disease and treatment, sexual function and other chemotherapy adverse effect subscales of the questionnaire. Correlations between EORTC QLQ-OV28 subscales and the total scores of BDI and STAI of the groups were statistically significant, except the sexual function subscale. CONCLUSION: The Turkish translated version of EORTC QLQ-OV28 module is a reliable, consistent, and a valid instrument for assessing the impact of treatment modalities on QoL among Turkish speaking women with ovarian cancer. Galenos Publishing 2020-03 2020-04-06 /pmc/articles/PMC7171542/ /pubmed/32341831 http://dx.doi.org/10.4274/tjod.galenos.2020.26594 Text en ©Copyright 2020 by Turkish Society of Obstetrics and Gynecology | Turkish Journal of Obstetrics and Gynecology published by Galenos Publishing House. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Investigation
Akdemir, Yeşim
Cam, Çetin
Ay, Nadiye Pınar
Karateke, Ateş
Validation of the Turkish version of European Organization for Research and Treatment of Cancer QLQ-OV28 ovarian cancer specific quality of life questionnaire
title Validation of the Turkish version of European Organization for Research and Treatment of Cancer QLQ-OV28 ovarian cancer specific quality of life questionnaire
title_full Validation of the Turkish version of European Organization for Research and Treatment of Cancer QLQ-OV28 ovarian cancer specific quality of life questionnaire
title_fullStr Validation of the Turkish version of European Organization for Research and Treatment of Cancer QLQ-OV28 ovarian cancer specific quality of life questionnaire
title_full_unstemmed Validation of the Turkish version of European Organization for Research and Treatment of Cancer QLQ-OV28 ovarian cancer specific quality of life questionnaire
title_short Validation of the Turkish version of European Organization for Research and Treatment of Cancer QLQ-OV28 ovarian cancer specific quality of life questionnaire
title_sort validation of the turkish version of european organization for research and treatment of cancer qlq-ov28 ovarian cancer specific quality of life questionnaire
topic Clinical Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171542/
https://www.ncbi.nlm.nih.gov/pubmed/32341831
http://dx.doi.org/10.4274/tjod.galenos.2020.26594
work_keys_str_mv AT akdemiryesim validationoftheturkishversionofeuropeanorganizationforresearchandtreatmentofcancerqlqov28ovariancancerspecificqualityoflifequestionnaire
AT camcetin validationoftheturkishversionofeuropeanorganizationforresearchandtreatmentofcancerqlqov28ovariancancerspecificqualityoflifequestionnaire
AT aynadiyepınar validationoftheturkishversionofeuropeanorganizationforresearchandtreatmentofcancerqlqov28ovariancancerspecificqualityoflifequestionnaire
AT karatekeates validationoftheturkishversionofeuropeanorganizationforresearchandtreatmentofcancerqlqov28ovariancancerspecificqualityoflifequestionnaire