Cargando…

MitoQ Modulates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction via Regulating Nrf2 Signaling

BACKGROUND: Gut barrier dysfunction with alterant mucosal permeability during sepsis is a challenge problem in clinical practice. Intestinal epithelial cells (IECs) are strongly involved in mucosal oxidative stress and inflammatory response. The current study aimed at investigating the effect of Mit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Shengfeng, Zhou, Qingniao, Li, Youcheng, Zhang, Yunli, Wu, Yinmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171662/ https://www.ncbi.nlm.nih.gov/pubmed/32351320 http://dx.doi.org/10.1155/2020/3276148

Ejemplares similares

MitoQ Is Able to Modulate Apoptosis and Inflammation
por: Piscianz, Elisa, et al.
Publicado: (2021)

Anthracycline-Induced Vascular Dysfunction: Is MitoQ the Answer?
por: Sawyer, Douglas B.
Publicado: (2020)

The mitochondrially targeted antioxidant MitoQ protects the intestinal barrier by ameliorating mitochondrial DNA damage via the Nrf2/ARE signaling pathway
por: Hu, Qiongyuan, et al.
Publicado: (2018)

MitoQ protects against hyperpermeability of endothelium barrier in acute lung injury via a Nrf2-dependent mechanism
por: Cen, Mengyuan, et al.
Publicado: (2021)

MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload
por: Ribeiro Junior, Rogério Faustino, et al.
Publicado: (2018)

MitoQ Loaded Chitosan-Hyaluronan Composite Membranes for Wound Healing
por: Tamer, Tamer M., et al.
Publicado: (2018)

Mitoquinone (MitoQ) Inhibits Platelet Activation Steps by Reducing ROS Levels
por: Méndez, Diego, et al.
Publicado: (2020)

MitoQ Inhibits Human Breast Cancer Cell Migration, Invasion and Clonogenicity
por: Capeloa, Tania, et al.
Publicado: (2022)

MitoQ Prevents Human Breast Cancer Recurrence and Lung Metastasis in Mice †
por: Capeloa, Tania, et al.
Publicado: (2022)

The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1
por: Xiao, Li, et al.
Publicado: (2016)

Does Antioxidant Mitoquinone (MitoQ) Ameliorate Oxidative Stress in Frozen–Thawed Rooster Sperm?
por: Sun, Lingwei, et al.
Publicado: (2022)

MitoQ Blunts Mitochondrial and Renal Damage during Cold Preservation of Porcine Kidneys
por: Parajuli, Nirmala, et al.
Publicado: (2012)

The targeted anti‐oxidant MitoQ causes mitochondrial swelling and depolarization in kidney tissue
por: Gottwald, Esther M., et al.
Publicado: (2018)

Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice
por: Gioscia-Ryan, Rachel A., et al.
Publicado: (2018)

The Effect of MitoQ on Aging-Related Biomarkers: A Systematic Review and Meta-Analysis
por: Braakhuis, Andrea J., et al.
Publicado: (2018)

The mitochondria-targeted antioxidant MitoQ, attenuates exercise-induced mitochondrial DNA damage
por: Williamson, Josh, et al.
Publicado: (2020)

Sex-Specific Effects of Nanoparticle-Encapsulated MitoQ (nMitoQ) Delivery to the Placenta in a Rat Model of Fetal Hypoxia
por: Ganguly, Esha, et al.
Publicado: (2019)

Mitochondrial-Targeted Antioxidant MitoQ Prevents E. coli Lipopolysaccharide-Induced Accumulation of Triacylglycerol and Lipid Droplets Biogenesis in Epithelial Cells
por: Fock, Ekaterina, et al.
Publicado: (2018)

Mitochondrial-Targeted Antioxidant MitoQ-Mediated Autophagy: A Novel Strategy for Precise Radiation Protection
por: Bao, Xingting, et al.
Publicado: (2023)

Protection against renal ischemia–reperfusion injury in vivo by the mitochondria targeted antioxidant MitoQ
por: Dare, Anna J., et al.
Publicado: (2015)

Exposing Mouse Oocytes to MitoQ During In Vitro Maturation Improves Maturation and Developmental Competence
por: Hosseinzadeh Shirzeyli, Maryam, et al.
Publicado: (2020)

Inhibition of Mitochondrial Redox Signaling with MitoQ Prevents Metastasis of Human Pancreatic Cancer in Mice
por: Capeloa, Tania, et al.
Publicado: (2022)

MitoQ Protects Ovarian Organoids against Oxidative Stress during Oogenesis and Folliculogenesis In Vitro
por: Wang, Jiapeng, et al.
Publicado: (2023)

Treating Neurodegenerative Disease with Antioxidants: Efficacy of the Bioactive Phenol Resveratrol and Mitochondrial-Targeted MitoQ and SkQ
por: Shinn, Lindsey J., et al.
Publicado: (2021)

The mitochondria‐targeted anti‐oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance
por: Kang, Liang, et al.
Publicado: (2020)

Prevention of diabetic nephropathy in Ins2(+/−AkitaJ) mice by the mitochondria-targeted therapy MitoQ
por: Chacko, Balu K., et al.
Publicado: (2010)

The Antioxidant MitoQ Protects Against CSE-Induced Endothelial Barrier Injury and Inflammation by Inhibiting ROS and Autophagy in Human Umbilical Vein Endothelial Cells
por: Chen, Sha, et al.
Publicado: (2019)

The mitochondria-targeted antioxidant MitoQ attenuated PM(2.5)-induced vascular fibrosis via regulating mitophagy
por: Ning, Ruihong, et al.
Publicado: (2021)

The Antioxidant Moiety of MitoQ Imparts Minimal Metabolic Effects in Adipose Tissue of High Fat Fed Mice
por: Bond, Simon T., et al.
Publicado: (2019)

MitoQ inhibits hepatic stellate cell activation and liver fibrosis by enhancing PINK1/parkin-mediated mitophagy
por: Dou, Shi-Ying, et al.
Publicado: (2021)

Mitochondria-Targeted Antioxidants MitoQ and MitoTEMPO Do Not Influence BRAF-Driven Malignant Melanoma and KRAS-Driven Lung Cancer Progression in Mice
por: Le Gal, Kristell, et al.
Publicado: (2021)

Mitochondria-targeted therapeutics, MitoQ and BGP-15, reverse aging-associated meiotic spindle defects in mouse and human oocytes
por: Al-Zubaidi, Usama, et al.
Publicado: (2020)

Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ(10), and angiotensin receptor blocker, losartan, on cardiovascular function
por: McLachlan, Jennifer, et al.
Publicado: (2014)

Inhibition of Mitochondrial ROS by MitoQ Alleviates White Matter Injury and Improves Outcomes after Intracerebral Haemorrhage in Mice
por: Chen, Weixiang, et al.
Publicado: (2020)

Regulatory effect of mitoQ on the mtROS-NLRP3 inflammasome pathway in leptin-pretreated BEAS-2 cells
por: Chong, Lei, et al.
Publicado: (2021)

Endurance training and MitoQ supplementation improve spatial memory, VEGF expression, and neurogenic factors in hippocampal tissue of rats
por: Zadeh, Hanzaleh Jafari, et al.
Publicado: (2022)

The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients
por: Escribano-Lopez, Irene, et al.
Publicado: (2016)

Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines
por: Dashdorj, Amarjargal, et al.
Publicado: (2013)

The mitochondria-targeted anti-oxidant MitoQ decreases ischemia-reperfusion injury in a murine syngeneic heart transplant model
por: Dare, Anna J., et al.
Publicado: (2015)

Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes
por: Ward, Micheal S., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_r9ngakc8foi505srgkf65fc9ca