Lattice complex assembled by noncompetitive anti-EGFR antibodies regulates actin cytoskeletal reorganization

BACKGROUND: Recent evidence of clinical trials highlights that the combination of two noncompetitive anti-EGFR antibodies can benefit patients with several cancers. Previous studies propose that a lattice complex assembled by antibodies and EGFR down-regulates surface EGFR by rapid internalization o...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Dianshuai, Lu, Tianqi, Du, Xingyu, Xi, Xi, Zhang, Xin, Zhang, Xitian, Zhang, Haoran, Sun, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171787/
https://www.ncbi.nlm.nih.gov/pubmed/32336949
http://dx.doi.org/10.1186/s12935-020-01204-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171787/
https://www.ncbi.nlm.nih.gov/pubmed/32336949
http://dx.doi.org/10.1186/s12935-020-01204-z

Ejemplares similares