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Lattice complex assembled by noncompetitive anti-EGFR antibodies regulates actin cytoskeletal reorganization
BACKGROUND: Recent evidence of clinical trials highlights that the combination of two noncompetitive anti-EGFR antibodies can benefit patients with several cancers. Previous studies propose that a lattice complex assembled by antibodies and EGFR down-regulates surface EGFR by rapid internalization o...
Autores principales: | Huang, Dianshuai, Lu, Tianqi, Du, Xingyu, Xi, Xi, Zhang, Xin, Zhang, Xitian, Zhang, Haoran, Sun, Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171787/ https://www.ncbi.nlm.nih.gov/pubmed/32336949 http://dx.doi.org/10.1186/s12935-020-01204-z |
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