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Suppression of peripheral NGF attenuates neuropathic pain induced by chronic constriction injury through the TAK1-MAPK/NF-κB signaling pathways

BACKGROUND: Anti-nerve growth factor (NGF) monoclonal antibodies (anti-NGF mAbs) have been reported to significantly attenuate pain, but the mechanism involved has not been fully elucidated, and the serious adverse events associated with mAbs seriously limit their clinical use. This study further in...

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Detalles Bibliográficos
Autores principales:	Dai, Wen-Ling, Yan, Bing, Bao, Yi-Ni, Fan, Ji-Fa, Liu, Ji-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171864/ https://www.ncbi.nlm.nih.gov/pubmed/32312253 http://dx.doi.org/10.1186/s12964-020-00556-3

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