Cargando…

Teduglutide for the treatment of adults with intestinal failure associated with short bowel syndrome: pooled safety data from four clinical trials

BACKGROUND: In multiple clinical studies, teduglutide reduced parenteral support (PS) with a consistent safety profile in adults with short bowel syndrome–associated intestinal failure (SBS–IF). The objective of this study was to assess adverse events (AEs) from a pooled data set. METHODS: Safety da...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pape, Ulrich-Frank, Iyer, Kishore R., Jeppesen, Palle B., Kunecki, Marek, Pironi, Loris, Schneider, Stéphane M., Seidner, Douglas L., Lee, Hak-Myung, Caminis, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171995/ https://www.ncbi.nlm.nih.gov/pubmed/32341691 http://dx.doi.org/10.1177/1756284820905766

Ejemplares similares

Enteral Autonomy and Days Off Parenteral Support With Teduglutide Treatment for Short Bowel Syndrome in the STEPS Trials
por: Seidner, Douglas L., et al.
Publicado: (2019)

Independence From Parenteral Nutrition and Intravenous Fluid Support During Treatment With Teduglutide Among Patients With Intestinal Failure Associated With Short Bowel Syndrome
por: Iyer, Kishore R., et al.
Publicado: (2016)

Long-Term Teduglutide for the Treatment of Patients With Intestinal Failure Associated With Short Bowel Syndrome
por: Schwartz, Lauren K, et al.
Publicado: (2016)

Impact of Teduglutide on Quality of Life Among Patients With Short Bowel Syndrome and Intestinal Failure
por: Chen, Kristina, et al.
Publicado: (2019)

Patients With Short Bowel on Narcotics During 2 Randomized Trials Have Abdominal Complaints Independent of Teduglutide
por: Fujioka, Ken, et al.
Publicado: (2016)

Teduglutide for short bowel syndrome
Publicado: (2020)

Targeted therapy of short-bowel syndrome with teduglutide: the new kid on the block
por: Vipperla, Kishore, et al.
Publicado: (2014)

Predictive Potential of Biomarkers of Intestinal Barrier Function for Therapeutic Management with Teduglutide in Patients with Short Bowel Syndrome
por: Büttner, Janine, et al.
Publicado: (2023)

Changes in Parenteral Nutrition Requirements and BMI in Patients with Parenteral Nutrition-Dependent Short Bowel Syndrome after Stopping Teduglutide—9 Years of Follow-Up
por: Zaczek, Zuzanna, et al.
Publicado: (2022)

Effect of Teduglutide, a Glucagon-like Peptide 2 Analog, on Citrulline Levels in Patients With Short Bowel Syndrome in Two Phase III Randomized Trials
por: Seidner, Douglas L, et al.
Publicado: (2015)

Identifying a subpopulation with higher likelihoods of early response to treatment in a heterogeneous rare disease: a post hoc study of response to teduglutide for short bowel syndrome
por: Chen, Kristina S, et al.
Publicado: (2018)

Quality of Life in Teduglutide-Treated Patients with Short Bowel Syndrome Intestinal Failure—A Nested Matched Pair Real-World Study
por: Blüthner, Elisabeth, et al.
Publicado: (2023)

Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome
por: Jeppesen, P B, et al.
Publicado: (2011)

Teduglutide in amyloidosis‐associated intestinal failure
por: Luhn, Clara, et al.
Publicado: (2023)

Effects of Teduglutide on Diarrhea in Pediatric Patients with Short Bowel Syndrome-Associated Intestinal Failure
por: Fifi, Amanda, et al.
Publicado: (2023)

Emerging treatment options for short bowel syndrome: potential role of teduglutide
por: Tee, Cheng T, et al.
Publicado: (2011)

Short Bowel Syndrome and Kidney Transplantation: Challenges, Outcomes, and the Use of Teduglutide
por: Abou Diwan, Elizabeth, et al.
Publicado: (2020)

Teduglutide in short bowel syndrome patients: A way back to normal life?
por: Harpain, Felix, et al.
Publicado: (2021)

Safety Findings in Pediatric Patients During Long‐Term Treatment With Teduglutide for Short‐Bowel Syndrome–Associated Intestinal Failure: Pooled Analysis of 4 Clinical Studies
por: Hill, Susan, et al.
Publicado: (2021)

Bridging intestinal failure with Teduglutide – A case report
por: Schlager, Lukas, et al.
Publicado: (2021)

Efficacy and Safety of Teduglutide in Infants and Children With Short Bowel Syndrome Dependent on Parenteral Support
por: Chiba, Masahiro, et al.
Publicado: (2023)

Teduglutide Promotes Epithelial Tight Junction Pore Function in Murine Short Bowel Syndrome to Alleviate Intestinal Insufficiency
por: Reiner, Johannes, et al.
Publicado: (2020)

Population pharmacokinetics and exposure‐response analyses of teduglutide in adult and pediatric patients with short bowel syndrome
por: Marier, Jean‐Francois, et al.
Publicado: (2021)

Gastric Foveolar Hyperplastic Polyps in 2 Children With Short Bowel Syndrome on Long-Term Teduglutide
por: Salazar, Jonathan A., et al.
Publicado: (2023)

Use of Teduglutide in Children With Intestinal Failure: A Systematic Review
por: Gigola, Francesca, et al.
Publicado: (2022)

Efficacy of Teduglutide for Parenteral Support Reduction in Patients with Short Bowel Syndrome: A Systematic Review and Meta-Analysis
por: Bioletto, Fabio, et al.
Publicado: (2022)

Improvement in metabolic indices including thyroid hormones via enhanced absorption of nutrients by Teduglutide in short bowel syndrome
por: Oba, Ken C., et al.
Publicado: (2022)

Safety and Efficacy of Teduglutide in Pediatric Patients With Intestinal Failure due to Short Bowel Syndrome: A 24‐Week, Phase III Study
por: Kocoshis, Samuel A., et al.
Publicado: (2019)

Efficacy, safety, and pharmacokinetics of teduglutide in adult Japanese patients with short bowel syndrome and intestinal failure: two phase III studies with an extension
por: Nakamura, Shiro, et al.
Publicado: (2022)

Post-Marketing Use of Teduglutide in a Large Cohort of Adults with Short Bowel Syndrome-Associated Chronic Intestinal Failure: Evolution and Outcomes
por: de Dreuille, Brune, et al.
Publicado: (2023)

Dose‐dependent elevation in amylase and lipase in response to teduglutide administration
por: Lee, Joshua, et al.
Publicado: (2019)

Efficacy of teduglutide in a patient with Crohn’s disease and short bowel syndrome on enteral nutrition: let’s start to think out of the box
por: Barberio, Brigida, et al.
Publicado: (2019)

Home parenteral nutrition with an omega-3-fatty-acid-enriched MCT/LCT lipid emulsion in patients with chronic intestinal failure (the HOME study): study protocol for a randomized, controlled, multicenter, international clinical trial
por: Klek, Stanislaw, et al.
Publicado: (2019)

SAT-LB86 Improvement In Metabolic Indices Including Thyroid HormonesVia Enhanced Absorption Of Nutrients By Teduglutide In Short Bowel Syndrome
por: Oba, Ken C, et al.
Publicado: (2020)

Short bowel syndrome – experience from a home parenteral nutrition centre
por: Braszczyńska-Sochacka, Joanna, et al.
Publicado: (2021)

The Role of a Colon-in-Continuity in Short Bowel Syndrome
por: Verbiest, Astrid, et al.
Publicado: (2023)

Case Report: Morphologic and Functional Characteristics of Intestinal Mucosa in a Child With Short Bowel Syndrome After Treatment With Teduglutide: Evidence in Favor of GLP-2 Analog Safety
por: Falco, Enrico Costantino, et al.
Publicado: (2022)

Expression, Purification and Characterization of Functional Teduglutide Using GST Fusion System in Prokaryotic Cells
por: Alizadeh, Ali Akbar, et al.
Publicado: (2023)

Impact of intestinal failure and parenteral support on adult patients with short‐bowel syndrome: A multinational, noninterventional, cross‐sectional survey
por: Jeppesen, Palle B., et al.
Publicado: (2022)

Impact on caregivers of adult patients receiving parenteral support for short‐bowel syndrome with intestinal failure: A multinational, cross‐sectional survey
por: Jeppesen, Palle B., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_h5cfel1qh6sf1dctu1ns2u595o