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Solid phase synthesis and biological evaluation of probestin as an angiogenesis inhibitor

Probestin is a potent aminopeptidase N (APN) inhibitor originally isolated from the bacterial culture broth. Here, we report probestin synthesis by solid phase peptide synthesis (SPPS) method and evaluated its activity to inhibit angiogenesis using a chicken embryo chorioallantoic membrane (CAM) ass...

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Detalles Bibliográficos
Autores principales:	Pathuri, Gopal, Thorpe, Jessica E., Disch, Bryan C., Bailey-Downs, Lora C., Ihnat, Michael A., Gali, Hariprasad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172075/ https://www.ncbi.nlm.nih.gov/pubmed/23664876 http://dx.doi.org/10.1016/j.bmcl.2013.04.031

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