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Extensive diversity and evolution of hepadnaviruses in bats in China

To better understand the evolution of hepadnaviruses, we sampled bats from Guizhou, Henan and Zhejiang provinces, China, and rodents from Zhejiang province. Genetically diverse hepadnaviruses were identified in a broad range of bat species, with an overall prevalence of 13.3%. In contrast, no rodent...

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Autores principales: Nie, Fang-Yuan, Lin, Xian-Dan, Hao, Zong-Yu, Chen, Xiao-Nan, Wang, Zhao-Xiao, Wang, Miao-Ruo, Wu, Jun, Wang, Hong-Wei, Zhao, Guoqiang, Ma, Runlin Z., Holmes, Edward C., Zhang, Yong-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172093/
https://www.ncbi.nlm.nih.gov/pubmed/29153861
http://dx.doi.org/10.1016/j.virol.2017.11.005
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author Nie, Fang-Yuan
Lin, Xian-Dan
Hao, Zong-Yu
Chen, Xiao-Nan
Wang, Zhao-Xiao
Wang, Miao-Ruo
Wu, Jun
Wang, Hong-Wei
Zhao, Guoqiang
Ma, Runlin Z.
Holmes, Edward C.
Zhang, Yong-Zhen
author_facet Nie, Fang-Yuan
Lin, Xian-Dan
Hao, Zong-Yu
Chen, Xiao-Nan
Wang, Zhao-Xiao
Wang, Miao-Ruo
Wu, Jun
Wang, Hong-Wei
Zhao, Guoqiang
Ma, Runlin Z.
Holmes, Edward C.
Zhang, Yong-Zhen
author_sort Nie, Fang-Yuan
collection PubMed
description To better understand the evolution of hepadnaviruses, we sampled bats from Guizhou, Henan and Zhejiang provinces, China, and rodents from Zhejiang province. Genetically diverse hepadnaviruses were identified in a broad range of bat species, with an overall prevalence of 13.3%. In contrast, no rodent hepadnaviruses were identified. The newly discovered bat hepadnaviruses fell into two distinct phylogenetic groups. The viruses within the first group exhibited high diversity, with some closely related to viruses previously identified in Yunnan province. Strikingly, the newly discovered viruses sampled from Jiyuan city in the second phylogenetic group were most closely related to those found in bats from West Africa, suggestive of a long-term association between bats and hepadnaviruses. A co-phylogenetic analysis revealed frequent cross-species transmission among bats from different species, genera, and families. Overall, these data suggest that there are likely few barriers to the cross-species transmission of bat hepadnaviruses.
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spelling pubmed-71720932020-04-22 Extensive diversity and evolution of hepadnaviruses in bats in China Nie, Fang-Yuan Lin, Xian-Dan Hao, Zong-Yu Chen, Xiao-Nan Wang, Zhao-Xiao Wang, Miao-Ruo Wu, Jun Wang, Hong-Wei Zhao, Guoqiang Ma, Runlin Z. Holmes, Edward C. Zhang, Yong-Zhen Virology Article To better understand the evolution of hepadnaviruses, we sampled bats from Guizhou, Henan and Zhejiang provinces, China, and rodents from Zhejiang province. Genetically diverse hepadnaviruses were identified in a broad range of bat species, with an overall prevalence of 13.3%. In contrast, no rodent hepadnaviruses were identified. The newly discovered bat hepadnaviruses fell into two distinct phylogenetic groups. The viruses within the first group exhibited high diversity, with some closely related to viruses previously identified in Yunnan province. Strikingly, the newly discovered viruses sampled from Jiyuan city in the second phylogenetic group were most closely related to those found in bats from West Africa, suggestive of a long-term association between bats and hepadnaviruses. A co-phylogenetic analysis revealed frequent cross-species transmission among bats from different species, genera, and families. Overall, these data suggest that there are likely few barriers to the cross-species transmission of bat hepadnaviruses. Published by Elsevier Inc. 2018-01-15 2017-11-16 /pmc/articles/PMC7172093/ /pubmed/29153861 http://dx.doi.org/10.1016/j.virol.2017.11.005 Text en © 2017 Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Nie, Fang-Yuan
Lin, Xian-Dan
Hao, Zong-Yu
Chen, Xiao-Nan
Wang, Zhao-Xiao
Wang, Miao-Ruo
Wu, Jun
Wang, Hong-Wei
Zhao, Guoqiang
Ma, Runlin Z.
Holmes, Edward C.
Zhang, Yong-Zhen
Extensive diversity and evolution of hepadnaviruses in bats in China
title Extensive diversity and evolution of hepadnaviruses in bats in China
title_full Extensive diversity and evolution of hepadnaviruses in bats in China
title_fullStr Extensive diversity and evolution of hepadnaviruses in bats in China
title_full_unstemmed Extensive diversity and evolution of hepadnaviruses in bats in China
title_short Extensive diversity and evolution of hepadnaviruses in bats in China
title_sort extensive diversity and evolution of hepadnaviruses in bats in china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172093/
https://www.ncbi.nlm.nih.gov/pubmed/29153861
http://dx.doi.org/10.1016/j.virol.2017.11.005
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