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Extensive diversity and evolution of hepadnaviruses in bats in China
To better understand the evolution of hepadnaviruses, we sampled bats from Guizhou, Henan and Zhejiang provinces, China, and rodents from Zhejiang province. Genetically diverse hepadnaviruses were identified in a broad range of bat species, with an overall prevalence of 13.3%. In contrast, no rodent...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172093/ https://www.ncbi.nlm.nih.gov/pubmed/29153861 http://dx.doi.org/10.1016/j.virol.2017.11.005 |
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author | Nie, Fang-Yuan Lin, Xian-Dan Hao, Zong-Yu Chen, Xiao-Nan Wang, Zhao-Xiao Wang, Miao-Ruo Wu, Jun Wang, Hong-Wei Zhao, Guoqiang Ma, Runlin Z. Holmes, Edward C. Zhang, Yong-Zhen |
author_facet | Nie, Fang-Yuan Lin, Xian-Dan Hao, Zong-Yu Chen, Xiao-Nan Wang, Zhao-Xiao Wang, Miao-Ruo Wu, Jun Wang, Hong-Wei Zhao, Guoqiang Ma, Runlin Z. Holmes, Edward C. Zhang, Yong-Zhen |
author_sort | Nie, Fang-Yuan |
collection | PubMed |
description | To better understand the evolution of hepadnaviruses, we sampled bats from Guizhou, Henan and Zhejiang provinces, China, and rodents from Zhejiang province. Genetically diverse hepadnaviruses were identified in a broad range of bat species, with an overall prevalence of 13.3%. In contrast, no rodent hepadnaviruses were identified. The newly discovered bat hepadnaviruses fell into two distinct phylogenetic groups. The viruses within the first group exhibited high diversity, with some closely related to viruses previously identified in Yunnan province. Strikingly, the newly discovered viruses sampled from Jiyuan city in the second phylogenetic group were most closely related to those found in bats from West Africa, suggestive of a long-term association between bats and hepadnaviruses. A co-phylogenetic analysis revealed frequent cross-species transmission among bats from different species, genera, and families. Overall, these data suggest that there are likely few barriers to the cross-species transmission of bat hepadnaviruses. |
format | Online Article Text |
id | pubmed-7172093 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71720932020-04-22 Extensive diversity and evolution of hepadnaviruses in bats in China Nie, Fang-Yuan Lin, Xian-Dan Hao, Zong-Yu Chen, Xiao-Nan Wang, Zhao-Xiao Wang, Miao-Ruo Wu, Jun Wang, Hong-Wei Zhao, Guoqiang Ma, Runlin Z. Holmes, Edward C. Zhang, Yong-Zhen Virology Article To better understand the evolution of hepadnaviruses, we sampled bats from Guizhou, Henan and Zhejiang provinces, China, and rodents from Zhejiang province. Genetically diverse hepadnaviruses were identified in a broad range of bat species, with an overall prevalence of 13.3%. In contrast, no rodent hepadnaviruses were identified. The newly discovered bat hepadnaviruses fell into two distinct phylogenetic groups. The viruses within the first group exhibited high diversity, with some closely related to viruses previously identified in Yunnan province. Strikingly, the newly discovered viruses sampled from Jiyuan city in the second phylogenetic group were most closely related to those found in bats from West Africa, suggestive of a long-term association between bats and hepadnaviruses. A co-phylogenetic analysis revealed frequent cross-species transmission among bats from different species, genera, and families. Overall, these data suggest that there are likely few barriers to the cross-species transmission of bat hepadnaviruses. Published by Elsevier Inc. 2018-01-15 2017-11-16 /pmc/articles/PMC7172093/ /pubmed/29153861 http://dx.doi.org/10.1016/j.virol.2017.11.005 Text en © 2017 Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Nie, Fang-Yuan Lin, Xian-Dan Hao, Zong-Yu Chen, Xiao-Nan Wang, Zhao-Xiao Wang, Miao-Ruo Wu, Jun Wang, Hong-Wei Zhao, Guoqiang Ma, Runlin Z. Holmes, Edward C. Zhang, Yong-Zhen Extensive diversity and evolution of hepadnaviruses in bats in China |
title | Extensive diversity and evolution of hepadnaviruses in bats in China |
title_full | Extensive diversity and evolution of hepadnaviruses in bats in China |
title_fullStr | Extensive diversity and evolution of hepadnaviruses in bats in China |
title_full_unstemmed | Extensive diversity and evolution of hepadnaviruses in bats in China |
title_short | Extensive diversity and evolution of hepadnaviruses in bats in China |
title_sort | extensive diversity and evolution of hepadnaviruses in bats in china |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172093/ https://www.ncbi.nlm.nih.gov/pubmed/29153861 http://dx.doi.org/10.1016/j.virol.2017.11.005 |
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