Novel and established intestinal cell line models – An indispensable tool in food science and nutrition

This review presents the applications of intestinal cell models of human and pig origin in food and nutritional sciences and highlights their potential as in vitro platforms for preclinical research. Intestinal cell models are used in studies of bioavailability, adsorption and transport in nutrition...

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Detalles Bibliográficos
Autores principales: Langerholc, Tomaz, Maragkoudakis, Petros A., Wollgast, Jan, Gradisnik, Lidija, Cencic, Avrelija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172287/
https://www.ncbi.nlm.nih.gov/pubmed/32336880
http://dx.doi.org/10.1016/j.tifs.2011.03.010
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author Langerholc, Tomaz
Maragkoudakis, Petros A.
Wollgast, Jan
Gradisnik, Lidija
Cencic, Avrelija
author_facet Langerholc, Tomaz
Maragkoudakis, Petros A.
Wollgast, Jan
Gradisnik, Lidija
Cencic, Avrelija
author_sort Langerholc, Tomaz
collection PubMed
description This review presents the applications of intestinal cell models of human and pig origin in food and nutritional sciences and highlights their potential as in vitro platforms for preclinical research. Intestinal cell models are used in studies of bioavailability, adsorption and transport in nutritional or toxicological settings, allergic effects of food components, as well as probiotics and/or host–pathogen gut interactions. In addition, this review discusses the advantages of using specialized and functional cell models over generic cancer-derived cell lines.
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spelling pubmed-71722872020-04-22 Novel and established intestinal cell line models – An indispensable tool in food science and nutrition Langerholc, Tomaz Maragkoudakis, Petros A. Wollgast, Jan Gradisnik, Lidija Cencic, Avrelija Trends Food Sci Technol Review This review presents the applications of intestinal cell models of human and pig origin in food and nutritional sciences and highlights their potential as in vitro platforms for preclinical research. Intestinal cell models are used in studies of bioavailability, adsorption and transport in nutritional or toxicological settings, allergic effects of food components, as well as probiotics and/or host–pathogen gut interactions. In addition, this review discusses the advantages of using specialized and functional cell models over generic cancer-derived cell lines. Elsevier Ltd. 2011-11 2011-04-09 /pmc/articles/PMC7172287/ /pubmed/32336880 http://dx.doi.org/10.1016/j.tifs.2011.03.010 Text en Copyright © 2011 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Langerholc, Tomaz
Maragkoudakis, Petros A.
Wollgast, Jan
Gradisnik, Lidija
Cencic, Avrelija
Novel and established intestinal cell line models – An indispensable tool in food science and nutrition
title Novel and established intestinal cell line models – An indispensable tool in food science and nutrition
title_full Novel and established intestinal cell line models – An indispensable tool in food science and nutrition
title_fullStr Novel and established intestinal cell line models – An indispensable tool in food science and nutrition
title_full_unstemmed Novel and established intestinal cell line models – An indispensable tool in food science and nutrition
title_short Novel and established intestinal cell line models – An indispensable tool in food science and nutrition
title_sort novel and established intestinal cell line models – an indispensable tool in food science and nutrition
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172287/
https://www.ncbi.nlm.nih.gov/pubmed/32336880
http://dx.doi.org/10.1016/j.tifs.2011.03.010
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