Human rhinovirus C—Associated severe pneumonia in a neonate

We present a case of severe pneumonia, associated with a prolonged infection by a species C rhinovirus (HRV) in a 3-week old neonate. HRV RNA was identified in nasal and nasopharyngeal secretions, bronchoalveolar lavage and bronchial specimens, stool and urine, collected from the patient during a on...

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Detalles Bibliográficos
Autores principales: Broberg, Eeva, Niemelä, Jussi, Lahti, Elina, Hyypiä, Timo, Ruuskanen, Olli, Waris, Matti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172304/
https://www.ncbi.nlm.nih.gov/pubmed/21342784
http://dx.doi.org/10.1016/j.jcv.2011.01.018
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author Broberg, Eeva
Niemelä, Jussi
Lahti, Elina
Hyypiä, Timo
Ruuskanen, Olli
Waris, Matti
author_facet Broberg, Eeva
Niemelä, Jussi
Lahti, Elina
Hyypiä, Timo
Ruuskanen, Olli
Waris, Matti
author_sort Broberg, Eeva
collection PubMed
description We present a case of severe pneumonia, associated with a prolonged infection by a species C rhinovirus (HRV) in a 3-week old neonate. HRV RNA was identified in nasal and nasopharyngeal secretions, bronchoalveolar lavage and bronchial specimens, stool and urine, collected from the patient during a one-month period. No other viral or bacterial agents were detected. Sequence analysis of two regions of the viral genome, amplified directly from the clinical specimens revealed a novel HRV-C variant. These observations highlight the occurrence of severe neonatal infections caused by HRVs and the need of rapid viral diagnostics for their detection.
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spelling pubmed-71723042020-04-22 Human rhinovirus C—Associated severe pneumonia in a neonate Broberg, Eeva Niemelä, Jussi Lahti, Elina Hyypiä, Timo Ruuskanen, Olli Waris, Matti J Clin Virol Article We present a case of severe pneumonia, associated with a prolonged infection by a species C rhinovirus (HRV) in a 3-week old neonate. HRV RNA was identified in nasal and nasopharyngeal secretions, bronchoalveolar lavage and bronchial specimens, stool and urine, collected from the patient during a one-month period. No other viral or bacterial agents were detected. Sequence analysis of two regions of the viral genome, amplified directly from the clinical specimens revealed a novel HRV-C variant. These observations highlight the occurrence of severe neonatal infections caused by HRVs and the need of rapid viral diagnostics for their detection. Elsevier B.V. 2011-05 2011-02-20 /pmc/articles/PMC7172304/ /pubmed/21342784 http://dx.doi.org/10.1016/j.jcv.2011.01.018 Text en Copyright © 2011 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Broberg, Eeva
Niemelä, Jussi
Lahti, Elina
Hyypiä, Timo
Ruuskanen, Olli
Waris, Matti
Human rhinovirus C—Associated severe pneumonia in a neonate
title Human rhinovirus C—Associated severe pneumonia in a neonate
title_full Human rhinovirus C—Associated severe pneumonia in a neonate
title_fullStr Human rhinovirus C—Associated severe pneumonia in a neonate
title_full_unstemmed Human rhinovirus C—Associated severe pneumonia in a neonate
title_short Human rhinovirus C—Associated severe pneumonia in a neonate
title_sort human rhinovirus c—associated severe pneumonia in a neonate
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172304/
https://www.ncbi.nlm.nih.gov/pubmed/21342784
http://dx.doi.org/10.1016/j.jcv.2011.01.018
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